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Outcome of cesarean scar pregnancy treated with local methotrexate injection
https://doi.org/10.18999/nagjms.82.1.15
https://doi.org/10.18999/nagjms.82.1.15766f9229-9038-4213-b915-8bde815a8d53
名前 / ファイル | ライセンス | アクション |
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03_Tam.pdf (638.6 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2020-02-26 | |||||
タイトル | ||||||
タイトル | Outcome of cesarean scar pregnancy treated with local methotrexate injection | |||||
言語 | en | |||||
著者 |
Le, Minh Tam
× Le, Minh Tam× Kotani, Tomomi× Tran, Manh Linh× Phan, Thi Minh Thu× Tran, Viet Khanh× Nguyen, Thi Kim Anh× Nguyen, Tran Thao Nguyen× Moriyama, Yoshinori× Yamamoto, Eiko× Nguyen, Vu Quoc Huy× Truong, Quang Vinh× Cao, Ngoc Thanh× Kikkawa, Fumitaka |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報Resource | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
権利情報 | Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | gestational sac | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | human chorionic gonadotropin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | transvaginal ultrasound | |||||
抄録 | ||||||
内容記述 | Local injection of methotrexate (MTX) has been widely used for caesarean scar pregnancy (CSP),but the optimal candidate remains undetermined. The aim of this study is to determine the risk factors associated with treatment failure among patients who received a single dose of local MTX. This is a retrospective cohort study. Clinical information was compared between treatment success vs. failure groups. Risk factors related to treatment failure were also investigated with multivariate analysis. Of 47 patients diagnosed with CSP, 30 received local MTX injection. The initial serum ß- human chorionic gonadotropin (hCG) level in the failure group was significantly higher than in the success group (p = 0.048), and the cut-off value was 47,000 mIU/ml. The rate of type 2 position of the gestational sac in the failure group was significantly higher than in the treatment success group (p = 0.031). A high initial serum ß-hCG level (≥ 47,000 mIU/ml) was identified as the independent risk factor for treatment failure (adjusted odds ratio = 21.9; 95% confidence interval = 1.3–383.1). Type 2 gestational sac position and a higher level of ß-hCG at diagnosis appear to be associated with poor outcomes after local injection of a single dose of MTX. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | This work was supported by JSPS KAKENHI (Grant Number: 15H02660). | |||||
言語 | en | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Nagoya University Graduate School of Medicine, School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.82.1.15 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/821.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 82, 号 1, p. 15-23, 発行日 2020-02 |
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著者版フラグ | ||||||
値 | publisher |