2024-02-28T03:42:43Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00003948
2023-11-16T06:42:35Z
499:508:509:516
Simple exponential regression model to describe the relation between minute ventilation and oxygen uptake during incremental exercise
Baba, Reizo
Mori, Emiko
Tauchi, Nobuo
Nagashima, Masami
open access
oxygen consumption,
ventilation
carbon dioxide
The physiological significance of an exponential regression model between minute ventilation (VE) and . oxygen uptake (VO2) during incremental exercise was examined. Thirty-eight subjects, including 12 patients with chronic heart failure, participated in cardiopulmonary exercise testing on a bicycle ergometer. The equation VE = a ebVO2, where a and b are parameters, was used to describe the relation between VE and VO2 during incremental exercise. Arterialized blood gas analysis was measured before and during exercise. The correlation coefficient of the regression model was high (r = 0.97±0.02). Parameter a negatively correlated with the arterial partial pressure of carbon dioxide during exercise (r=-0.44, p<0.01), and positively corre-lated with peak VO2 (r=0.47, p<0.01). Parameter b negatively correlated with peak VO2 (r=-0.86, p<0.01) and positively correlated with the dead space to tidal volume ratio (r=0.68, p<0.01). The regression model, as well as parameters a and b, is physiologically useful in expressing metabolic response to exercise. This model, a specific solution to the differential equation dVE/dVO2=bVE, implies that the more a subject breathes, the greater is the increment in ventilation needed to meet a further increment of metabolic demand.
Nagoya University School of Medicine
2002-11
eng
departmental bulletin paper
VoR
https://doi.org/10.18999/nagjms.65.3-4.95
http://hdl.handle.net/2237/5381
https://nagoya.repo.nii.ac.jp/records/3948
10.18999/nagjms.65.3-4.95
2186-3326
0027-7622
Nagoya Journal of Medical Science
65
3-4
95
102
https://nagoya.repo.nii.ac.jp/record/3948/files/nj6533.pdf
application/pdf
67.4 kB
2018-02-19