2024-03-29T15:44:11Z
https://nagoya.repo.nii.ac.jp/oai
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2023-01-16T03:53:07Z
320:321:322
グロビンフォールドタンパク質における二次構造ブレイカとしての電荷反転対称性
Secondary Structure Breaker and Charge Symmetry in Globin Fold Proteins
今井, 賢一郎
IMAI, Kenichiro
美宅, 成樹
MITAKU, Shigeki
open access
Secondary structure breakers impose strong limitations on the global structure of a protein. Four kinds of secondary structure breakers (proline, glycine, small polar residues and amphiphilic residues) were revealed previously (Imai & Mitaku, 2005, 2007). In addition, the inverse charge symmetry, which drives the formation of hairpin structures, was studied in globin fold proteins, typical all-α type proteins. The inverse charge symmetries were positioned at about two thirds of loops region that do not contain the predicted breakers. Therefore, the charge symmetry is the most plausible mechanism for the fifth type of breaker. The distribution pattern of secondary structure breakers in the remote-homologous globin fold proteins showed that the same fold are realized breaking the secondary structures by various patterns of the breakers.
豊田理化学研究所
2007
jpn
journal article
AM
http://hdl.handle.net/2237/9346
https://nagoya.repo.nii.ac.jp/records/7642
0372-039X
豊田研究報告
60
225
229
https://nagoya.repo.nii.ac.jp/record/7642/files/imai_mitaku.pdf
application/pdf
218.2 kB
2018-02-19