2024-03-29T02:10:52Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00014181
2023-11-16T06:24:28Z
499:508:509:616
A CASE OF SEX REVERSAL SYNDROME WITH SEX-DETERMINING REGION (XX MALE)
YAMAMOTO, MASANORI
YOKOI, KEISUKE
KATSUNO, SATOSHI
HIBI, HATSUKI
MIYAKE, KOJI
open access
XX male
Infertility
Sex determining region
We examined a 32-year-old man with a 4-year history of infertility. The man's sex life, male hair pattern, and penis were normal, and he had no history of erection problems. Left and right testicular volumes were 2 ml and 3 ml, respectively. Semen analysis showed no sperm. The endocrine panel revealed increased serum luteinizing hormone and follicle-stimulating hormone levels, and a normal serum testosterone level. A testicular biopsy demonstrated that both Leydig cell and Sertoli cell hyperplasia were present, and that no germ cells were found in the tubules. A chromosome analysis done on the peripheral blood lymphocytes revealed a karyotype of 46, XX. We identified the sex-determining region, Y, by polymerase chain reaction using Y-specific probes in this patient. The diagnosis was XX male.
Nagoya University School of Medicine
1995-12-25
eng
departmental bulletin paper
VoR
https://doi.org/10.18999/nagjms.58.3-4.111
http://hdl.handle.net/2237/16086
https://nagoya.repo.nii.ac.jp/records/14181
10.18999/nagjms.58.3-4.111
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5834/5834.html
2186-3326
0027-7622
Nagoya Journal of Medical Science
58
3-4
111
115
https://nagoya.repo.nii.ac.jp/record/14181/files/v58n34p107_110.pdf
application/pdf
725.3 kB
2018-02-20