2024-03-28T10:31:47Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00014186
2023-11-16T06:24:38Z
499:508:509:616
ASSESSMENT OF THE EFFECTS OF AGING AND MEDICATION ON SALIVARY GLAND FUNCTION IN PATIENTS WITH XEROSTOMIA USING 99mTC-SCINTIGRAPHY
KAGAMI, HIDEAKI
HAYASHI, TSUNETOSHI
SHlGETOMI, TOSHIO
UEDA, MINORU
open access
Xerostomia
99mTc-scintigraphy
Unstimulated whole saliva
Aging
Medication
To examine the effect of aging and medication on xerostomia, the salivary gland function was evaluated in 20 patients with xerostomia using 99mTc-scintigraphy and the measurement of unstimulated whole saliva (USWS). All of the patients showed USWS volume of less than 2ml/10min. The patients were divided into 2 subgroups based on age (under 65 and 65 and older) and medication status (patients who were on medication which reduced salivary secretion and patients who were not on such medication). The scintigraphic results, such as the maximum radioisotope (RI) count, RI secretion velocity and the volume of USWS, were compared between the subgroups. The maximum RI count and the RI secretory velocity in the submandibular gland and the volume of USWS revealed significantly different functional disturbances between relatively younger patients (under 65) and older patients (65 and older). There was no difference when the scintigraphic results and the volume of USWS measurements in medicated patients were compared with the results of similar tests performed on non-medicated patients. When the medicated and non-medicated groups were separated by age, an increase in age still diminished the volume of USWS in medicated patients. This result might be related to an organic change in the submandibular gland in older patients which was suggested by the scintigraphic results.
Nagoya University School of Medicine
1995-12-25
eng
departmental bulletin paper
VoR
https://doi.org/10.18999/nagjms.58.3-4.149
http://hdl.handle.net/2237/16091
https://nagoya.repo.nii.ac.jp/records/14186
10.18999/nagjms.58.3-4.149
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5834/5834.html
2186-3326
0027-7622
Nagoya Journal of Medical Science
58
3-4
149
155
https://nagoya.repo.nii.ac.jp/record/14186/files/v58n34p149_155.pdf
application/pdf
432.2 kB
2018-02-20