2024-03-29T05:59:37Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00016646
2023-11-16T05:30:45Z
499:508:509:1522
The Role of Mast Cells in Human Liver Cirrhosis
KIM, U
open access
Mast cells appear to play significant roles in physiological and pathological conditions. Some functions of mast cells may relate to liver cirrhosis, which is characterized by degeneration, necrosis and regeneration of parenchyma as well as fibrosis, but little information regarding this association has been obtained. This study was carried out in order to clarify the pathogenesis of liver cirrhosis as related to the distribution and the role of mast cells. Fifty-five cases of liver cirrhosis were divided into five groups, according to Kim's morphological classification and the mean values with the standard errors in each group were determined with regard to the number of mast cells, the relative volume of the trabecula and the liver weight. A statistical analysis of these determinations was also performed. The results of the present investigation revealed that a greater number of mast cells were found in the I-B and the II-B groups in which a more marked regeneration was histopathologically recognized, and that in these groups a statistically significant correlation existed between the number of mast cells and the liver weight which mostly increased with regeneration. These findings strongly suggested that mast cells in human liver cirrhosis had a close relation- ship to regeneration of hepatic parenchyma followed by occasional incidence of malignant hepatomas.
Nagoya University School of Medicine
1971-09
eng
departmental bulletin paper
VoR
https://doi.org/10.18999/nagjms.34.2.131
http://hdl.handle.net/2237/18689
https://nagoya.repo.nii.ac.jp/records/16646
10.18999/nagjms.34.2.131
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/342/342.html
2186-3326
0027-7622
Nagoya Journal of Medical Science
34
2
131
142
https://nagoya.repo.nii.ac.jp/record/16646/files/v34n2p131_142.pdf
application/pdf
1.7 MB
2018-02-20