2024-03-29T08:15:01Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00017964
2023-01-16T04:06:18Z
320:321:322
NUMERICAL SIMULATION ON FLOW IN COLUMN CHROMATOGRAPHY
YAMAMOTO, KAZUHIRO
KOMIYAMA, RYO
UMEMURA, TOMONARI
open access
Electronic version of an article published as [International Journal of Modern Physics C. v.24, n.12, 2013, p.1340003] [Article DOI:10.1142/S0129183113400032] © [copyright World Scientific Publishing Company] [http://www.worldscientific.com/worldscinet/ijmpc]
Porous media
chromatography
numerical simulations
LBM
Monolithic columns have attracted much attention as a novel platform for high throughput analysis, but there is little information about the fluid profile in the flow channels. In this paper, we presented our approach for the fluid simulation in column chromatography by the lattice Boltzmann method (LBM). To simulate the monolithic column system, the calculation domain was modeled by the 3D channel flow through sphere obstacles. Several types of porous structure were used, with uniform and nonuniform pores. Based on the simulations results, we discussed fluid flow and pressure variation for the optimization of the suitable structure for HPLC system.
World Scientific Publishing
2013-12
eng
journal article
AM
http://hdl.handle.net/2237/20053
https://nagoya.repo.nii.ac.jp/records/17964
https://doi.org/10.1142/S0129183113400032
0129-1831
International Journal of Modern Physics C
24
12
1340003
1340003
https://nagoya.repo.nii.ac.jp/record/17964/files/117.pdf
application/pdf
1.1 MB
2018-02-21