2024-03-28T23:48:32Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00022940
2023-11-16T04:46:49Z
499:508:509:1930
A multicenter survey of stage T1 glottic cancer treated with radiotherapy delivered in 2.25-Gy fractions in clinical practice : An initial 5-year analysis
Itoh, Yoshiyuki
Kubota, Seiji
Kawamura, Mariko
Nomoto, Yoshihito
Murao, Takayuki
Yamakawa, Kouji
Ishihara, Shunichi
Hirasawa, Naoki
Asano, Akiko
Yanagawa, Shigeo
Naganawa, Shinji
open access
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
T1 glottic cancer
radiotherapy
fraction size
hypofractionation
The purpose of this study was to evaluate the acute and late toxicity as well as local control (LC) in T1 glottic cancer (GC) patients treated with hypofractionated radiotherapy (RT) in clinical practice. The Tokai Study Group for Therapeutic Radiology and Oncology started RT treatment with a dose of 2.25 Gy for T1 GC in 2011. Ten institutions combined data from 104 patients with T1 squamous cell carcinoma between 2011 and 2015. In total, 104 patients with T1 GC were irradiated with a standard radiation dose of 63 Gy in 28 fractions.The median follow-up duration was 18 (3.7–49.5) months. Acute grade 3 adverse events were observed in 7 patients, with 4 patients (5%) having dermatitis and 3 patients (4%) having mucositis. Late adverse events above grade 3 were not observed. Two patients developed local recurrence. The rates of acute adverse events in the present study were comparable to those in previous studies that have used 2 Gy fractions of RT.
Nagoya University Graduate School of Medicine, School of Medicine
2016-11
eng
departmental bulletin paper
VoR
https://doi.org/10.18999/nagjms.78.4.399
http://hdl.handle.net/2237/25120
https://nagoya.repo.nii.ac.jp/records/22940
10.18999/nagjms.78.4.399
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/784.html
2186-3326
0027-7622
Nagoya Journal of Medical Science
78
4
399
406
https://nagoya.repo.nii.ac.jp/record/22940/files/15_Itoh.pdf
application/pdf
174.5 kB
2018-02-22