2024-03-28T13:32:28Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00025284
2023-11-16T04:18:24Z
499:508:509:2063
Clinical significance of gastrointestinal patency evaluation by using patency capsule in Crohn’s disease
Yoshimura, Toru
Hirooka, Yoshiki
Nakamura, Masanao
Watanabe, Osamu
Yamamura, Takeshi
Matsushita, Masanobu
Ishikawa, Takuya
Furukawa, Kazuhiro
Funasaka, Kohei
Ohno, Eizaburo
Kawashima, Hiroki
Miyahara, Ryoji
Goto, Hidemi
open access
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
capsule endoscopy
patency
Crohn’s disease
small bowel
Capsule endoscopy (CE) enables noninvasive visualization of the small bowel in Crohn’s disease (CD), but should not be conducted in patients with bowel obstruction. Patency capsule (PC) can be ingested before conducting the CE examination to ensure patency of the gastrointestinal (GI) tract. This study aimed to evaluate the clinical significance of GI patency which the PC demonstrated. A retrospective review of the medical records was conducted with 99 consecutive patients with CD who underwent PC and CE at Nagoya University Hospital from January 2010 to May 2015. By using the Cox proportional hazards model, the association between the GI patency evaluated using the PC and the outcome in terms of the rate of patients who needed admission or surgery during the 2-year follow-up was examined. Of all 99 patients who ingested the PC, 84 (84.8%) were diagnosed as not having bowel obstruction, and therefore were eligible for CE (P group). Of the 15 patients in whom bowel obstruction was suspected (NP group), 12 patients underwent either the balloon-assisted endoscopy (n=10) or enteroclysis (n=2), and 11 were confirmed to have small bowel stricture. Non-admission rates of the P and NP groups during the 2-year observation period were 74/84 (88.0%) and 8/15 (53.3%), respectively (P<0.001). Non-operation rates of the P and NP groups during the 2-year observation period were 80/84 (95.2%) and 9/15 (60.0%), respectively (P<0.001). In conclusion, GI patency as diagnosed using the PC was associated with a significantly lower incidence of admission or surgical intervention.
Nagoya University Graduate School of Medicine, School of Medicine
2018-02
eng
departmental bulletin paper
VoR
https://doi.org/10.18999/nagjms.80.1.121
http://hdl.handle.net/2237/00027496
https://nagoya.repo.nii.ac.jp/records/25284
10.18999/nagjms.80.1.121
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/801.html
2186-3326
0027-7622
Nagoya Journal of Medical Science
80
1
121
128
https://nagoya.repo.nii.ac.jp/record/25284/files/13_Yoshimura.pdf
application/pdf
423.9 kB
2018-03-19