2024-03-29T01:51:38Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00027949
2023-01-16T04:50:42Z
1917:1918:1919
Pd/TiO2-Photocatalyzed Self-Condensation of Primary Amines To Afford Secondary Amines at Ambient Temperature
Wang, Lyu-Ming
Kobayashi, Kensuke
Arisawa, Mitsuhiro
Saito, Susumu
Naka, Hiroshi
open access
“This document is the Accepted Manuscript version of a Published Work that appeared in final form in [Organic Letters], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [https://pubs.acs.org/articlesonrequest/AOR-GpPimqbZIJJwsDGf2Ht8].”
Symmetric secondary amines were synthesized by the self-condensation of primary amines over a palladium-loaded titanium dioxide (Pd/TiO2) photocatalyst. The reactions afforded a series of secondary amines in moderate to excellent isolated yields at ambient temperature (30 °C, in cyclopentyl methyl ether). Applicability for one-pot pharmaceutical synthesis was demonstrated by a photocatalytic reaction sequence of self-condensation of an amine followed by N-alkylation of the resulting secondary amine with an alcohol.
ファイル公開:2020-01-18
ACS Publications
2019-01-18
eng
journal article
AM
http://hdl.handle.net/2237/00030148
https://nagoya.repo.nii.ac.jp/records/27949
https://doi.org/10.1021/acs.orglett.8b03271
1523-7060
Organic Letters
21
2
341
344
https://nagoya.repo.nii.ac.jp/record/27949/files/8Y08LMW_WOM.pdf
application/pdf
495.0 kB
2020-01-18