2024-03-29T15:47:44Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00028737
2023-11-16T02:59:04Z
499:508:509:2445
Diagnostic contribution of cytological examination to endobronchial ultrasound-guided transbronchial biopsy for lung malignancies
Kajikawa, Shigehisa
Imai, Naoyuki
Okachi, Shotaro
Yatsuya, Hiroshi
Souma, Tomohide
Watanabe, Toshikazu
Goto, Yasuhiro
Minezawa, Tomoyuki
Hashimoto, Naozumi
Imaizumi, Kazuyoshi
Hasegawa, Yoshinori
open access
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
bronchoscopy
guide sheath
cytology
diagnostic yield
bronchial brushing
Although endobronchial ultrasound guided transbronchial biopsy (TBB) with a guide sheath (EBUS-GS) is widely used for diagnosis of peripheral pulmonary lesions, the diagnostic contribution of cytology (bronchial brushing, bronchial washing and biopsy forceps rinse) has not been established. To determine the diagnostic contribution of cytological examination to EBUS-GS-TBB, we reviewed medical records of patients with lung malignancies who had undergone TBB with EBUS-GS (EBUS-GS group, n=187) or TBB without EBUS-GS (conventional TBB [CTBB] group, n=197) at Nagoya University Hospital. Although the mean size of target lesions was significantly larger in the CTBB group than the EBUS-GS group, the total diagnostic rate was equivalent between two groups (EBUS-GS: 73.3%, CTBB: 66.0%). In the EBUS-GS group, cytological procedures increased the diagnostic rate by 9.1% (17/137), compared with only 4.1% (8/130) in the CTBB group. Sensitivity of cytology among biopsy-negative patients was significantly higher in EBUS-GS group than CTBB group (P=0.022). Furthermore, in the EBUS-GS group, among 17 patients whose malignant diagnoses could only be established cytologically, bronchial brushing contributed to the malignant diagnosis in 64.7% (11/17). These data may suggest that cytological examination, especially bronchial brushing, may be an important diagnostic contributor in EBUS-GS-TBB.
Nagoya University Graduate School of Medicine, School of Medicine
2019-11
eng
departmental bulletin paper
VoR
https://doi.org/10.18999/nagjms.81.4.613
http://hdl.handle.net/2237/00030924
https://nagoya.repo.nii.ac.jp/records/28737
10.18999/nagjms.81.4.613
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/814.html
2186-3326
0027-7622
Nagoya Journal of Medical Science
81
4
613
620
https://nagoya.repo.nii.ac.jp/record/28737/files/07_Kajikawa.pdf
application/pdf
359.7 kB
2019-11-26