2024-03-29T10:47:35Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00030968
2023-11-16T02:44:36Z
499:508:509:2601
Testosterone deficiency syndrome among males with type 2 diabetes mellitus in East Malaysia
Ahmad, Saharuddin
Jerampang, Peter
Tohid, Hizlinda
Ali, Mohd Fairuz
Jamil, Teh Rohaila
Kong, Christopher Ho Chee
open access
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
diabetes mellitus
testosterone deficiency syndrome
Malaysia
Type 2 diabetes mellitus (T2DM) may be independently associated with testosterone deficiency syndrome (TDS). Both conditions are linked with reduced quality of life and cardiovascular comorbidities. The magnitude of TDS among T2DM men and its predictors has still not been well established in Malaysia. This study aimed to determine the prevalence of TDS and its predictors among men with T2DM attending a government health clinic in Kuching, Sarawak. TDS severity and level of serum total testosterone were also explored. A cross-sectional study was conducted involving 360 respondents. Aging Males Symptoms Scale (AMS) score > 26 and serum total testosterone ≤ 12 nmol/L were used to diagnose TDS. The prevalence of TDS in current study was 19.7%. Multivariate analysis showed that determinants for TDS included age (Adjusted OR 1.061: 95% CI 1.020; 1.103), Iban ethnicity (Adjusted OR 2.469: 95% CI 1.154; 5.283) and a waist circumference equal or greater than 90 cm (Adjusted OR 3.655: 95% CI 1.472; 9.081). However, there was no significant association between TDS and the level of serum total testosterone (p = 0.581). We concluded that the prevalence of TDS in this study was relatively low. The severity of this condition may not be influenced by testosterone level. Physicians might consider a diagnosis of TDS if elder diabetic men with abdominal obesity present to primary care clinics with clinical features of hypogonadism. Health care providers also might consider lowering their threshold to screen for TDS among Iban men with T2DM.
Nagoya University Graduate School of Medicine, School of Medicine
2020-11
eng
departmental bulletin paper
VoR
https://doi.org/10.18999/nagjms.82.4.613
http://hdl.handle.net/2237/00033153
https://nagoya.repo.nii.ac.jp/records/30968
10.18999/nagjms.82.4.613
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/824.html
2186-3326
0027-7622
Nagoya Journal of Medical Science
82
4
613
621
https://nagoya.repo.nii.ac.jp/record/30968/files/02_Ahmed.pdf
application/pdf
595.2 kB
2020-11-26