2024-03-29T01:46:41Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:02001904
2023-01-16T04:41:04Z
499:500:501
Effects of Aerobic, Resistance, or Combined Exercise Training Among Older Adults with Subjective Memory Complaints: A Randomized Controlled Trial
Makino, Taeko
Umegaki, Hiroyuki
Ando, Masahiko
Cheng, Xian Wu
Ishida, Koji
Akima, Hiroshi
Oshida, Yoshiharu
Yoshida, Yasuko
Uemura, Kazuki
Shimada, Hiroyuki
Kuzuya, Masafumi
open access
Amnesia
cognition
cognitive dysfunction
executive function
exercise
memory
physical activity
randomized controlled trial
resistance training
wechsler memory scale
Background:Physical exercise is suggested to be effective for preventing cognitive decline in older adults, but the relative efficacy of different types of exercise have yet to be clarified. Objective:This single-blinded randomized controlled trial was designed to investigate the differential effects of aerobic exercise training (AT), resistance exercise training (RT), and combined exercise training (CT) on cognition in older adults with subjective memory complaints (SMC). Methods:Community-dwelling older adults with SMC (n = 415; mean age = 72.3 years old) were randomly assigned to one of the four groups: AT, RT, CT, or control group. The study consisted of two phases: a 26-week intervention and a 26-week follow-up. The participants were evaluated at baseline, 26 weeks (postintervention), and 52 weeks (follow-up). The primary outcome of this study was memory function, which was assessed using the Logical Memory II subtest of the Wechsler Memory Scale-Revised (WMS-R) score. The secondary outcomes included global cognitive function, verbal fluency, working memory, processing speed, and executive functions. Results:Intention-to-treat analysis by a mixed-effect model repeated measure showed that the AT group had significantly improved performance on the WMS-R Logical Memory II test (2.74 [1.82–3.66] points) than the control group (1.36 [0.44–2.28] points) at the postintervention assessment (p = 0.037). The effect was more pronounced in those without amnesia than those with amnesia. No significant improvement was observed in the RT and CT groups. Conclusion:This study suggests that AT intervention can improve delayed memory in community-dwelling older adults, particularly in individuals without objective memory decline.
IOS Press
2021-07-21
eng
journal article
AM
http://hdl.handle.net/2237/0002001904
https://nagoya.repo.nii.ac.jp/records/2001904
https://doi.org/10.3233/JAD-210047
1387-2877
Journal of Alzheimer's Disease
82
2
701
717
https://nagoya.repo.nii.ac.jp/record/2001904/files/Manuscript_JAD_fin.pdf
application/pdf
963 KB
2022-01-12