2024-03-28T09:28:20Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:02001950
2023-06-05T04:04:17Z
320:321:322
Carbon nanotubes reinforced with natural/synthetic polymers to mimic the extracellular matrices of bone – a review
Arumugam, S.
Ju, Y.
open access
© 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
The persistent failure of conventional materials used in manufacturing orthopedic implants was due to the deficiency or poor integrations of implant materials to the juxtaposed bone and stress-strain imbalances between the interfaces of tissues and implant materials. Therefore, the fabrication of a suitable bioactive scaffold for bone tissue engineering is considered a vital requisite to mimic the extracellular bone matrix. Numerous researches were reported concerning the fabrication of a suitable bioactive scaffold to improve cell adhesion, proliferation, and differentiation so far. However, for the past two decades, the research on carbon nanotubes (CNTs)-reinforced composites employed in the biomedical field is increasing day-by-day because of its outstanding properties. Moreover, it is essential to choose a biocompatible polymer with greater affinity to act as an extracellular matrix as well as to attract CNTs and in facilitating the homogeneous distribution of CNTs in aqueous and organic solvents. The development of CNTs-based composites in bone tissue engineering is presented in this review based on the last 10 years of research. The detailed information about the structural-functions and defects of bone, and the importance of CNTs-functionalized natural and synthetic polymers, and their potential activity in bone regenerations and bone replacements have been reviewed.
Elsevier
2023-06-01
2021-06
eng
journal article
AM
http://hdl.handle.net/2237/0002001950
https://nagoya.repo.nii.ac.jp/records/2001950
https://doi.org/10.1016/j.mtchem.2020.100420
2468-5194
Materials Today Chemistry
20
100420
https://nagoya.repo.nii.ac.jp/record/2001950/files/MTCHEM-D-20-00537_R1-1.pdf
application/pdf
4.3 MB
2023-06-01