2024-03-28T10:13:01Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:02005866
2023-05-09T00:18:02Z
1213:1620:1621:1682316489289
肥満者におけるインスリン抵抗性と高血圧に関する研究 : 身体トレーニング前後の比較
Relationship between insulin resistance and hypertension : Effect of physical training
押田, 芳治
OSHIDA, Yoshiharu
佐藤, 祐造
SATO, Yuzo
近藤, 孝晴
KONDO, Takaharu
戸田, 安士
TODA, Yasushi
伊藤, 章
ITO, Akira
佐藤, 寿一
SATO, Juichi
大沢, 功
OHSAWA, Isao
坂本, 信夫
SAKAMOTO, Nobuo
木村, 正剛
KIMURA, Seigo
open access
To clarify relationship between insulin resistance and hypertension in obesity using the euglycemic clamp technique, eight nondiabetic obese subjects were studied before and after weight reduction following dietary restriction and physical exercise therapy. The following results were obtained. 1) Insulin sensitivity significantly improved from 2.93±0.34ml/kg/min to 6.03±1.23ml/kg/min (P<0.05). At the same time, systolic, diastolic and mean blood pressure were significantly decreased from 141±6.98±4 and 114±4mmHg to 121±4 (P< 0.005), 79±3 (P<0.005) and 93±3mmHg (P<0.001), respectively. 2) Before reduction, insulin sensitivity was inversely related to systolic (r=-0.744, P<0.05), diastolic (r=-0.861, P<0.01) or mean blood pressure (r=-0.857, P<0.01). These results suggest that the severity of insulin resistance in obesity is directly correlated with that of hypertension and that not only dietary restriction but also physical exercise training is very effective on the improvement of insulin insensitivity and blood pressure.
名古屋大学総合保健体育科学センター
The Research Center of Health, Physical Fitness and Sports, Nagoya University
1990-03-26
jpn
departmental bulletin paper
VoR
https://doi.org/10.18999/njhpfs.13.1.55
http://hdl.handle.net/2237/0002005866
https://nagoya.repo.nii.ac.jp/records/2005866
10.18999/njhpfs.13.1.55
0289-5412
総合保健体育科学
Nagoya Journal of Health, Physical Fitness & Sports
13
1
55
59
https://nagoya.repo.nii.ac.jp/record/2005866/files/njhpfs_13_1_55.pdf
application/pdf
2.6 MB
2023-04-26