2024-03-29T09:25:24Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:02006067
2023-05-11T06:11:58Z
1213:1620:1621:1683613699480
代謝性疾患の運動療法に関する研究 第二報 : 糖尿病者の軽運動負荷時における代謝変動
Studies on the Physical Exercise Treatment for the Metabolic Disorders (2) : Metabolic Changes during and after Light Exercise in Diabetics
早水, サヨ子
HAYAMIZU, Sayoko
佐藤, 祐造
SATO, Yuzo
山本, 親
YAMAMOTO, Chikashi
大桑, 哲男
OHKUWA, Tetsuo
戸田, 安士
TODA, Yasushi
伊藤, 章
ITO, Akira
open access
Physical exercise has been considered benefical in the treatment of diabetes for many years. In poorly controlled, especially, ketotic diabetics, however, physical exercise results in more pronounced hyperglycemia, hyperlipidemia and hyperketonemia. But the mechanism of physical exercise has never been studied in detail. This study was performed to clarify the effect of physical exercise on the metabolic and hormonal changes in patients with diabetes mellitus in order to establish the biochemical criteria of physical exercise treatment. 100g glucose was administered to 5 healthy subjects, 4 mild and 4 severe diabetics. Furthermore, exercise-glucose tolerance tests were carried out using treadmill walking with a speed of 70 m/min for 30 minutes during 60 to 90 minutes following oral administration of 100g glucose, and the data were compared respectively with those of glucose tolerance tests. The magnitude of decrease of blood glucose and insulin levels tended to be lower in the severe diabetics than in the mild diabetics, and also, to be lower in the mild diabetics than in the healthy subjects. In contrast, the total ketone body concentrations increased 30 minutes after exercise in severe diabetics. Physical exercise did not produce any significant changes in the other metabolites and hormones. In one of the severe diabetics whose insulin values remained at a low level, physical exercise became a stressor and the hypercaloraemic state induced further hypercaloraemia, because the blood glucose, FFA and total ketone body levels increased after exercise. It is concluded that only well controlled diabetic patients can participate in physical exercise treatment, confirming that insulin may exert a permissive effect on exercise-induced glucose uptake.
名古屋大学総合保健体育科学センター
The Research Center of Health, Physical Fitness and Sports, Nagoya University
1983-03-31
jpn
departmental bulletin paper
VoR
https://doi.org/10.18999/njhpfs.6.1.63
http://hdl.handle.net/2237/0002006067
https://nagoya.repo.nii.ac.jp/records/2006067
10.18999/njhpfs.6.1.63
0289-5412
総合保健体育科学
Nagoya Journal of Health, Physical Fitness & Sports
6
1
63
71
https://nagoya.repo.nii.ac.jp/record/2006067/files/njhpfs_6_1_63.pdf
application/pdf
5.3 MB
2023-05-11