2024-03-28T11:35:14Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00012291
2023-11-16T06:35:52Z
499:508:509:1277
Tissue-Engineering Bone from Omentum
Kamei, Yuzuru
38839
Toriyama, Kazuhiro
38840
Takada, Toru
38841
Yagi, Shunjiro
38842
Omentum
Bone
Tissue-engineering
Reconstruction
2010-08
Tissue engineering of bone is an interesting field of research. Many approaches to bone tissue engineering such as from bone marrow stromal cells in vitro have been reported. Furthermore, a model of vascularized tissue-engineered bone flap has been reported. However, there has been no report of bone tissue engineering using omentum. We present a study of tissue engineering of bone from omentum in a rabbit model. The omentum, which was elevated based on the right gastroepiploic vessels, was wrapped by the periosteum from cranial bone in the abdomen of rabbits. We harvested the omentum thus wrapped 1, 2, 4, 6, 8, 12, or 24 weeks after surgery. Within 1 week after surgery, woven bone was formed and clusters of osteoblasts were observed. At 8 weeks, medullization, including the presence of granulocytes, was confirmed. This technique might prove useful for creating tissue-engineered bone flaps for reconstructive surgery.
departmental bulletin paper
Nagoya University School of Medicine
2010-08
Nagoya Journal of Medical Science
3-4
72
111
117
http://hdl.handle.net/2237/14172
2186-3326
0027-7622
eng