2024-03-28T14:02:52Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00014803
2023-11-16T06:25:30Z
499:508:509:1403
MORPHOLOGIC CHARACTERIZATION AND QUANTIFICATION OF SUPERFICIAL CALCIFICATIONS OF THE CORONARY ARTERY : IN VIVO ASSESSMENT USING OPTICAL COHERENCE TOMOGRAPHY
MATSUMOTO, MASAYA
45731
YOSHIKAWA, DAIJI
45732
ISHII, HIDEKI
45733
HAYAKAWA, SEIICHI
45734
TANAKA, MIHO
45735
KUMAGAI, SOICHIRO
45736
HAYASHI, MUTSUHARU
45737
MUROHARA, TOYOAKI
45738
Coronary artery disease
Calcium
Angina pectoris
2012-08
Coronary calcification is proportional to the extent and severity of atherosclerotic disease, and is a predictor of cardiac events. Furthermore, coronary calcification protruding into the lumen is considered as one type of vulnerable plaque. Optical coherence tomography (OCT) can provide in vivo imaging of the detailed vessel wall structure of the coronary artery with high resolution, as in the histological approach. We analyzed coronary calcification in that fashion using OCT in vivo. This study consisted of 70 superficial coronary calcifications of 39 consecutive patients who underwent percutaneous coronary intervention. After revascularization, OCT was performed in the treated vessel. We analyzed morphologic characteristics and the quantification of OCT-determined coronary calcification. Superficial coronary calcifications were classified into two groups depending on whether they did not intrude the lumen (type I) or did (type II). The distance from the lumen and the volume of each calcification were then measured. Superficial coronary calcifications were classified into two groups; type I, n = 39 (56%) and type II, n = 31 (44%). Type II calcifications were located significantly closer to the lumen [80 μm (60–130) vs.130 μm (90–260), p = 0.015], and tended to be smaller, but did not show a significant difference [0.65 (0.26–1.3) mm3 vs. 1.2 (0.47–1.9) mm3, p = 0.153] compared to those of type I. In conclusion, OCT could visualize superficial coronary calcifications in detail and enable us to evaluate in vivo morphologic characterizations and quantify them.
departmental bulletin paper
Nagoya University School of Medicine
2012-08
Nagoya Journal of Medical Science
3-4
74
253
260
http://hdl.handle.net/2237/16736
2186-3326
0027-7622
eng
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7434/7434.html