2024-03-28T08:38:45Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00016573
2023-11-16T05:40:45Z
499:508:509:1512
Studies on Multilayer Membrane Artificial Lung
IIZUKA, SATOSHI
96229
1969-03
Studies were carried out to devise a new multilayer membrane artifiilal lung. It was determined from the present studies on flow patterns and dye clearance that the basic design of the multilayer membrane artificial lung should have one-inlet and one-outlet and be elliptic in shape. Many little projections were made on both surfaces of a distributing mat in order to support membranes and to give turbulences to the flowing blood. Distance between two membranes or the thickness of the blood layer was determined to be 0.8-0.9 mm. Fifty Hs silicon rubber was used as material for the distributing mats in order to prevent blood leakage from between the membranes. Silicon rubber membrane and Teflon membrane were investigated for gas permeability by using a model of the elliptic artificial lung and a model of the Peirce-Galletti's artificial lung. Nineteen mongrel dogs were subjected to the studies. Phycon membrane or silicon rubber membrane, made in Japan, showed an excellent gas exchange capability and proved to be the best membrane now available. One unit of the artificial lung comprises two mats and two membranes, having an oxygenating surface area of 1540 ㎠. This elliptic membrane artificial lung with a stack of ten oxygenating units has approximately 60 ml/min of oxygen uptake when Phycon membrane is used, and can be applied to total cardio- pulmonary bypass for infants and small children.
departmental bulletin paper
Nagoya University School of Medicine
1969-03
Nagoya Journal of Medical Science
3-4
31
467
483
2186-3326
0027-7622
eng
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/3134/3134.html