2024-03-28T14:45:26Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00019158
2023-11-16T05:21:22Z
499:508:509:1674
Evaluation of Emphysema Using Three-Dimensional Computed Tomography: Association with Postoperative Complications in Lung Cancer Patients
KAWAKAMI, KENICHI
56013
IWANO, SHINGO
56014
HASHIMOTO, NAOZUMI
56015
HASEGAWA, YOSHINORI
56016
NAGANAWA, SHINJI
56017
Chronic obstructive pulmonary disease
Lung cancer
Thoracic surgery
Postoperative complication
Computed tomography
2015-02
Three-dimensional computed tomography (3D-CT) enables in vivo volumetry of total lung volume (TLV) and emphysematous low-attenuation volume (LAV) in patients with chronic obstructive pulmonary disease (COPD). We retrospectively investigated the correlation between preoperative 3D-CT volumetry and postoperative complications in lung cancer patients. We searched our institution’s surgical records from December 2006 to December 2009 and selected patients who had undergone pulmonary lobectomy for primary lung cancer. From 3D-CT data, TLV and LAV <–950 HU of thresholds were retrospectively measured. The LAV% was calculated as follows: LAV% = LAV/TLV*100. The associations between the seven independent variables (LAV%, age, gender, body mass index, smoking history, forced expiratory volume in 1 second as percent forced vital capacity [FEV1%], and resected lobe) and the two outcomes (postoperative complications and prolonged postoperative stay [PPS]) were compared using logistic regression analysis. A total of 309 patients (222 males, 87 females; mean age, 67 years; range, 40–87 years) were evaluated. On multivariate analysis, age and LAV% were significantly correlated with postoperative complications (p = 0.006 and p = 0.006, respectively), and LAV% was significantly correlated with PPS (p = 0.031). LAV% measured using 3D-CT is more sensitive for predicting complications after lobectomy for lung cancer than FEV1%.
departmental bulletin paper
Nagoya University School of Medicine
2015-02
Nagoya Journal of Medical Science
1-2
77
113
122
http://hdl.handle.net/2237/21264
2186-3326
0027-7622
eng
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7712.html