2024-03-29T01:04:17Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00023438
2023-01-16T04:13:14Z
499:500:501
Hyperamylasemia and pancreatitis following posterior spinal surgery
Kobayashi, Kazuyoshi
69581
Imagama, Shiro
69582
Ito, Zenya
69583
Ando, Kei
69584
Shinjo, Ryuichi
69585
Yagi, Hideki
69586
Hida, Tetsuro
69587
Ito, Kenyu
69588
Ishikawa, Yoshimoto
69589
Ishiguro, Naoki
69590
Background: Postoperative pancreatitis has primarily been reported as a complication of abdominal surgery, but there are some case reports of postoperative pancreatitis after spinal surgery. The objective of this study was to investigate a case series of hyperamylasemia and pancreatitis following posterior spinal surgery. Methods: The serum amylase level was measured following posterior spinal surgery in the prone position. Patients were divided into groups with a normal serum amylase level (0–125 IU/L) and with hyperamylasemia (>125 IU/L), based on the upper limit of normal of 125 IU/L in our institution. Relationships among preoperative factors, perioperative factors, and the serum amylase level were investigated. Results: Hyperamylasemia (serum amylase >125 IU/L) following posterior spinal surgery was found in 92 cases (35 %). Among perioperative factors, intraoperative estimated blood loss (EBL) and operating time were significantly higher in patients with high serum amylase than in patients with normal serum amylase (P < 0.01). In a multivariate regression model, intraoperative EBL (OR 1.001, 95 % CI 1.000–1.002; P = 0.001) and operation time (OR 1.006, 95 % CI 1.003–1.009; P = 0.006) were significantly associated with postoperative pancreatitis. Serum amylase levels of ≥5 times the upper limit of normal were found in six cases. Five of these cases were asymptomatic and one was caused by severe pancreatitis. Conclusions: In our case series, intraoperative blood loss caused a rise in the serum amylase level following posterior spinal surgery. Thus, this level should be carefully monitored after spinal surgery with significant blood loss. Clinical symptoms of pancreatitis, such as abdominal pain and vomiting, should also be monitored following spinal surgery.
journal article
Springer
2015-11
application/pdf
Journal of Orthopaedic Science
6
20
967
972
http://doi.org/10.1007/s00776-015-0754-0
http://hdl.handle.net/2237/25634
0949-2658
https://nagoya.repo.nii.ac.jp/record/23438/files/Hyperamylasemia_and_pancreatitis.pdf
eng
https://doi.org/10.1007/s00776-015-0754-0
The final publication is available at Springer via http://doi.org/10.1007/s00776-015-0754-0