2024-03-28T14:05:51Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00023562
2023-01-16T04:12:59Z
499:500:501
Differentiation of Spinal Schwannomas and Myxopapillary Ependymomas: MR Imaging and Pathologic Features
Ando, Kei
70047
Imagama, Shiro
70048
Ito, Zenya
70049
Hirano, Kenichi
70050
Tauchi, Ryoji
70051
Muramoto, Akio
70052
Matsui, Hiroki
70053
Matsumoto, Tomohiro
70054
Sakai, Yoshihito
70055
Matsuyama, Yukihiro
70056
Ishiguro, Naoki
70057
MR imaging
pathologic features
spinal schwannomas
myxopapillary ependymomas
differentiation
STUDY DESIGN: Retrospective clinical study. OBJECTIVE: The objective of this study is to evaluate magnetic resonance imaging and pathologic features of spinal schwannomas (SCHs) and myxopapillary ependymomas (MPEs) with focus on differentiating 2 disease entities. SUMMARY OF BACKGROUND DATA: Few studies have reported on the differentiation of SCHs and MPEs. METHODS: Fifty-three patients were retrospectively reviewed with histologically confirmed spinal SCHs (41 patients) or MPEs (12 patients) of the cauda equina and/or conus medullaris. We evaluated neurological deterioration after surgery in association with the intraoperative findings of the tumor, as well as with the preoperative magnetic resonance images and postoperative histologic findings. RESULTS: Patients in the SCH group had a greater mean age at surgery and a greater mean disease duration. In the SCH group, all 24 tumors that were homogeneously hyperintense on the T2-weighted (T2W) images showed rim enhancement on the postcontrast T1-weighted (T1W) images. Moreover, all 14 of the SCHs with homogeneous enhancement on the postcontrast T1W images were isointense on the T2W images. However, in the MPE group, all 8 of the tumors that were homogeneously hyperintense on T2W images showed homogeneous enhancement on their postcontrast T1W images. CONCLUSIONS: It is very important to differentiate SCHs and MPEs before surgery, because there are reported cases of dissemination of MPEs through cerebrospinal fluid throughout the neuraxis; the tumor must be removed en block to prevent this. Although MPEs and SCHs may have similar imaging characteristics, detailed examination of the magnetic resonance T2W image and postcontrast T1W image facilitates their differentiation.
journal article
Lippincott Williams & Wilkins
2014-04
application/pdf
Journal of Spinal Disorders & Techniques
2
27
105
110
http://doi.org/10.1097/BSD.0b013e31825017aa
http://hdl.handle.net/2237/25759
1536-0652
https://nagoya.repo.nii.ac.jp/record/23562/files/No126ando.pdf
eng
https://doi.org/10.1097/BSD.0b013e31825017aa
This is a non-final version of an article published in final form in (Journal of Spinal Disorders & Techniques. v.27, n.2, 2014, p.105-110).