2024-03-28T10:19:35Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00026353
2023-01-16T04:16:15Z
320:321:322
The ortho-substituent on 2,4-bis(trifluoromethyl)phenylboronic acid catalyzed dehydrative condensation between carboxylic acids and amines
Wang, Ke
85215
Lu, Yanhui
85216
Ishihara, Kazuaki
85217
2,4-Bis(trifluoromethyl)phenylboronic acid is a highly effective catalyst for dehydrative amidation between carboxylic acids and amines. Mechanistic studies suggest that a 2 : 2 mixed anhydride is expected to be the only active species, and the ortho-substituent of boronic acid plays a key role in preventing the coordination of amines to the boron atom of the active species, thus accelerating the amidation. This catalyst works for α-dipeptide synthesis.
ファイル公開:2019-05-28
journal article
Royal Society of Chemistry
2018-05-28
application/pdf
Chemical Communications
43
54
5410
5413
1359-7345
1364-548X
https://nagoya.repo.nii.ac.jp/record/26353/files/revised manuscript.pdf
eng
https://doi.org/10.1039/C8CC02558D