2024-03-28T21:38:54Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00027056
2023-01-16T04:17:50Z
643:666:667
Toward a Synthesis of Fawcettimine-Type Lycopodium Alkaloids: Stereocontrolled Synthesis of a Functionalized Azaspirocycle Precursor
Huang, Wen-Yu
88634
Nishikawa, Toshio
88635
Nakazaki, Atsuo
88636
The stereocontrolled synthesis of a new azaspirocycle precursor of the fawcettimine-type Lycopodium alkaloids is described. Our approach provides an efficient entry to the azaspirocycle via a cascade Wacker-allylation sequence followed by a highly stereoselective Claisen rearrangement. This azaspirocycle, bearing all of the requisite functionality with pivotal stereogenic centers, is considered to be a versatile precursor useful for the fawcettimine-type Lycopodium alkaloids.
ファイル公開:2019-09-21
journal article
ACS Publications
2018-09-21
application/pdf
The Journal of Organic Chemistry
18
83
11108
11117
0022-3263
1520-6904
https://nagoya.repo.nii.ac.jp/record/27056/files/revised_main_text_180728d.pdf
eng
https://doi.org/10.1021/acs.joc.8b01719
“This document is the Accepted Manuscript version of a Published Work that appeared in final form in [The Journal of Organic Chemistry], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [https://pubs.acs.org/articlesonrequest/AOR-BeWqHcS67iRJzc2hBadn].”