2024-03-28T15:35:13Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00028737
2023-11-16T02:59:04Z
499:508:509:2445
Diagnostic contribution of cytological examination to endobronchial ultrasound-guided transbronchial biopsy for lung malignancies
Kajikawa, Shigehisa
94417
Imai, Naoyuki
94418
Okachi, Shotaro
94419
Yatsuya, Hiroshi
94420
Souma, Tomohide
94421
Watanabe, Toshikazu
94422
Goto, Yasuhiro
94423
Minezawa, Tomoyuki
94424
Hashimoto, Naozumi
94425
Imaizumi, Kazuyoshi
94426
Hasegawa, Yoshinori
94427
bronchoscopy
guide sheath
cytology
diagnostic yield
bronchial brushing
2019-11
Although endobronchial ultrasound guided transbronchial biopsy (TBB) with a guide sheath (EBUS-GS) is widely used for diagnosis of peripheral pulmonary lesions, the diagnostic contribution of cytology (bronchial brushing, bronchial washing and biopsy forceps rinse) has not been established. To determine the diagnostic contribution of cytological examination to EBUS-GS-TBB, we reviewed medical records of patients with lung malignancies who had undergone TBB with EBUS-GS (EBUS-GS group, n=187) or TBB without EBUS-GS (conventional TBB [CTBB] group, n=197) at Nagoya University Hospital. Although the mean size of target lesions was significantly larger in the CTBB group than the EBUS-GS group, the total diagnostic rate was equivalent between two groups (EBUS-GS: 73.3%, CTBB: 66.0%). In the EBUS-GS group, cytological procedures increased the diagnostic rate by 9.1% (17/137), compared with only 4.1% (8/130) in the CTBB group. Sensitivity of cytology among biopsy-negative patients was significantly higher in EBUS-GS group than CTBB group (P=0.022). Furthermore, in the EBUS-GS group, among 17 patients whose malignant diagnoses could only be established cytologically, bronchial brushing contributed to the malignant diagnosis in 64.7% (11/17). These data may suggest that cytological examination, especially bronchial brushing, may be an important diagnostic contributor in EBUS-GS-TBB.
departmental bulletin paper
Nagoya University Graduate School of Medicine, School of Medicine
2019-11
Nagoya Journal of Medical Science
4
81
613
620
2186-3326
0027-7622
eng
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/814.html
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International