2024-03-29T10:16:06Z
https://nagoya.repo.nii.ac.jp/oai
oai:nagoya.repo.nii.ac.jp:00029361
2023-11-16T03:00:12Z
499:508:509:2478
Pathological changes of the myocardium in reworsening of anthracycline-induced cardiomyopathy after explant of a left ventricular assist device
Hiraiwa, Hiroaki
96377
Okumura, Takahiro
96378
Shimizu, Shinya
96379
Arao, Yoshihito
96380
Oishi, Hideo
96381
Kato, Hiroo
96382
Kuwayama, Tasuku
96383
Yamaguchi, Shogo
96384
Haga, Tomoaki
96385
Yokoi, Tsuyoshi
96386
Kondo, Toru
96387
Sugiura, Yuki
96388
Kano, Naoaki
96389
Watanabe, Naoki
96390
Fukaya, Kenji
96391
Furusawa, Kenji
96392
Sawamura, Akinori
96393
Morimoto, Ryota
96394
Fujimoto, Kazuro
96395
Mutsuga, Masato
96396
Usui, Akihiko
96397
Murohara, Toyoaki
96398
anthracycline-induced cardiomyopathy
left ventricular assist device
cardiac pathology
reworsening heart failure
2020-02
We herein report the long-term changes in cardiac function and pathological findings after successful explantation of a left ventricular assist device in a 42-year-old patient with anthracycline-induced cardiomyopathy with reworsening heart failure. Endomyocardial biopsy samples revealed that the cardiomyocyte diameter decreased and collagen volume fraction increased just after left ventricular assist device explantation. The collagen volume fraction decreased after 6 months, despite preserved systolic function. At 5 years after left ventricular assist device explantation, the systolic function markedly decreased and cardiomyocyte diameter increased. Pathological changes of the myocardium may enable the identification of cardiac dysfunction prior to echocardiographic changes in patients with reworsening heart failure after left ventricular assist device explantation.
departmental bulletin paper
Nagoya University Graduate School of Medicine, School of Medicine
2020-02
Nagoya Journal of Medical Science
1
82
129
134
2186-3326
0027-7622
eng
http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/821.html
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International