{"created":"2021-03-01T06:17:24.311310+00:00","id":10569,"links":{},"metadata":{"_buckets":{"deposit":"ef522a6b-1112-43f6-bfd3-651a723761f2"},"_deposit":{"id":"10569","owners":[],"pid":{"revision_id":0,"type":"depid","value":"10569"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00010569","sets":["336:635:636"]},"author_link":["32015","32016"],"item_12_alternative_title_19":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"GENERAL SYNTHESIS OF C-NUCLEOSIDES","subitem_alternative_title_language":"en"}]},"item_12_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1983-04-30","bibliographicIssueDateType":"Issued"}}]},"item_12_date_granted_64":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"1983-04-30"}]},"item_12_degree_grantor_62":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"名古屋大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"Nagoya University"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"13901","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_12_degree_name_61":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"理学博士","subitem_degreename_language":"ja"}]},"item_12_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The stereocontrolled, general synthesis of C-nucleosides starting from inexpensive non-carbohydrate substances has been accomplished. Construction of' the ribose skeleton, a key operation,relies on the efficiency of the [3 + 4] cyclocoupling reaction between polybromo ketones and furans aided by low-valent transition metals which leads to 8-oxabicyclo[3.2.1]octan-3-one structures. Pseudouridine and its analogues such as 2-thiopseudouridine,pseudoisocytidine, 6-azapseudouridine, and 6-aza-2-thiopseudouridine have been synthesized from (1R,6S,7S,8R)-7,8-isopropylidenedioxy-3,9-dioxabicyclo[4.2.l^l,6]nonan-4-one. Showdomycin is also obtainable from the common intermediate. A variety of pyrimidine C-nucleosides bearing branched-chain sugars have been synthesized starting from adequately substituted (lR*,6S*,7S*,8R*)-7,8-isopropylidenedioxy-3,9- dioxabicyclo[4.2.1^1,6]nonan-4-ones in only three steps. In addition, the straightforward synthesis of homo-C-nucleosides has been achieved, which allows the synthesis of homopseudouridine, homoshowdomycin, homopyrazomycin, etc.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_12_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"名古屋大学博士学位論文 学位の種類 : 理学博士(課程) 学位授与年月日 : 昭和58年4月30日","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_12_dissertation_number_65":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第1586号"}]},"item_12_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/12410"}]},"item_12_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_12_text_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_text_value":"application/pdf"},{"subitem_text_value":"application/pdf"}]},"item_12_text_63":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_text_value":"1983"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐藤, 恒夫","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"32015","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sato, Tsuneo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"32016","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"ko1586.pdf","filesize":[{"value":"9.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ko1586.pdf ","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/10569/files/ko1586.pdf"},"version_id":"077ef6f6-9c61-4634-99ef-f9bb3c3e6d0a"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"ko1586_abstr.pdf","filesize":[{"value":"124.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ko1586_abstr.pdf ","objectType":"abstract","url":"https://nagoya.repo.nii.ac.jp/record/10569/files/ko1586_abstr.pdf"},"version_id":"b11100ee-07b1-466b-b085-340a2663b02b"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"C-ヌクレオシドの一般合成法","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"C-ヌクレオシドの一般合成法","subitem_title_language":"ja"}]},"item_type_id":"12","owner":"1","path":["636"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-12-16"},"publish_date":"2009-12-16","publish_status":"0","recid":"10569","relation_version_is_last":true,"title":["C-ヌクレオシドの一般合成法"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T03:56:28.096885+00:00"}