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Multidimensional theory of protein folding
http://hdl.handle.net/2237/12626
http://hdl.handle.net/2237/1262686956c49-f96b-4552-b6ef-ffc651435902
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-01-20 | |||||
タイトル | ||||||
タイトル | Multidimensional theory of protein folding | |||||
言語 | en | |||||
著者 |
Itoh, Kazuhito
× Itoh, Kazuhito× Sasai, Masaki |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | Copyright (2009) American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior per mission of the author and the American Institute of Physics. | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | biochemistry | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | free energy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | molecular biophysics | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | molecular configurations | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | proteins | |||||
抄録 | ||||||
内容記述 | Theory of multidimensional representation of free energy surface of protein folding is developed byadopting structural order parameters of multiple regions in protein as multiple coordinates. Various scenarios of folding are classified in terms of cooperativity within individual regions and interactions among multiple regions and thus obtained classification is used to analyze the folding process of several example proteins. Ribosomal protein S6, src-SH3 domain, CheY, barnase, and BBL domain are analyzed with the two-dimensional representation by using a structure-based Hamiltonian model. The extension to the higher dimensional representation leads to the finer description of the folding process. Barnase, NtrC, and an ankyrin repeat protein are examined with the three-dimensional representation. The multidimensional representation allows us to directly address questions on folding pathways, intermediates, and transition states. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | American Institite of Physics | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1063/1.3097018 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0021-9606 | |||||
書誌情報 |
en : THE JOURNAL OF CHEMICAL PHYSICS 巻 130, 号 4, p. 145104-145104, 発行日 2009-04-13 |
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フォーマット | ||||||
application/pdf | ||||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/12626 | |||||
識別子タイプ | HDL | |||||
URI | ||||||
識別子 | http://dx.doi.org/10.1063/1.3097018 | |||||
識別子タイプ | DOI |