{"created":"2021-03-01T06:18:00.994345+00:00","id":11142,"links":{},"metadata":{"_buckets":{"deposit":"b7bd51bb-1068-4ced-8d53-c13c0df57754"},"_deposit":{"id":"11142","owners":[],"pid":{"revision_id":0,"type":"depid","value":"11142"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00011142"},"item_10_biblio_info_6":{"attribute_name":"\u66f8\u8a8c\u60c5\u5831","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"244","bibliographicPageStart":"236","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"European Journal of Pain"}]}]},"item_10_description_4":{"attribute_name":"\u6284\u9332","attribute_value_mlt":[{"subitem_description":"Chronic muscle pain of the neck, shoulder and low back is quite common and often related to a stressed condition. In this study we tried to make a model of long-lasting muscle mechanical hyperalgesia based on one type of stress, repeated cold stress (RCS) (Kita T, Hata T, Yoneda R, Okage T. Stress state caused by alternation of rhythm in environmental temperature, and the functional disorders in mice and rats. Folia Pharmacol Jpn 1975;71:195\u2013210). We first validated a method of measuring the muscle mechanical nociceptive threshold through skin, with surface anesthesia of the skin covering the muscle. We found that a pressure test using a Randall\u2013Selitto analgesiometer equipped with a larger probe ( 2.6 mm) can measure the deep mechanical withdrawal threshold even under the presence of cutaneous punctuate hyperalgesia. RCS was performed by changing the temperature from 22 \u00b0C to either 4 \u00b0C (RCS at 4 \u00b0C) or \u22123 \u00b0C (RCS at \u22123 \u00b0C) every 30 min, and then maintained at 4 \u00b0C/\u22123 \u00b0C from 17:30 to 10:00 the next day. RCS at 4 \u00b0C for 5 days induced bilateral deep mechanical hyperalgesia lasting 2\u20133 weeks without cutaneous punctuate hyperalgesia. Deep mechanical hyperalgesia observed after RCS at \u22123 \u00b0C lasted longer (6 weeks) and was severer than RCS at 4 \u00b0C. Bilateral cutaneous punctuate hyperalgesia was also observed with RCS at \u22123 \u00b0C. Intramuscular injection of lidocaine confirmed that the muscle was hyperalgesic. RCS might serve as a useful model for study of the mechanism of chronic muscle pain and its treatment.","subitem_description_type":"Abstract"}]},"item_10_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/13012"}]},"item_10_publisher_32":{"attribute_name":"\u51fa\u7248\u8005","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_10_select_15":{"attribute_name":"\u8457\u8005\u7248\u30d5\u30e9\u30b0","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"10903801","subitem_source_identifier_type":"ISSN"}]},"item_10_text_14":{"attribute_name":"\u30d5\u30a9\u30fc\u30de\u30c3\u30c8","attribute_value_mlt":[{"subitem_text_value":"application/pdf"},{"subitem_text_value":"application/pdf"}]},"item_creator":{"attribute_name":"\u8457\u8005","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nasu, Teruaki"}],"nameIdentifiers":[{"nameIdentifier":"33712","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Taguchi, Toru"}],"nameIdentifiers":[{"nameIdentifier":"33713","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mizumura, Kazue"}],"nameIdentifiers":[{"nameIdentifier":"33714","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"\u30d5\u30a1\u30a4\u30eb\u60c5\u5831","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"nasu_manuscript.pdf","filesize":[{"value":"183.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"nasu_manuscript.pdf ","url":"https://nagoya.repo.nii.ac.jp/record/11142/files/nasu_manuscript.pdf"},"version_id":"8869cf18-ecf6-4be1-9631-b88736222266"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"nasu_graph.pdf","filesize":[{"value":"171.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"nasu_graph.pdf ","url":"https://nagoya.repo.nii.ac.jp/record/11142/files/nasu_graph.pdf"},"version_id":"6701371c-09f2-42ab-8ac3-7a2052aa8958"}]},"item_keyword":{"attribute_name":"\u30ad\u30fc\u30ef\u30fc\u30c9","attribute_value_mlt":[{"subitem_subject":"Muscular mechanical hyperalgesia","subitem_subject_scheme":"Other"},{"subitem_subject":"Skeletal muscle","subitem_subject_scheme":"Other"},{"subitem_subject":"Repeated cold stress","subitem_subject_scheme":"Other"},{"subitem_subject":"Chronic muscle pain","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"\u8a00\u8a9e","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"\u8cc7\u6e90\u30bf\u30a4\u30d7","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats","item_titles":{"attribute_name":"\u30bf\u30a4\u30c8\u30eb","attribute_value_mlt":[{"subitem_title":"Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats"}]},"item_type_id":"10","owner":"1","path":["329/330/331"],"pubdate":{"attribute_name":"\u516c\u958b\u65e5","attribute_value":"2010-03-29"},"publish_date":"2010-03-29","publish_status":"0","recid":"11142","relation_version_is_last":true,"title":["Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2021-03-01T19:12:11.558730+00:00"}