{"created":"2021-03-01T06:19:56.328307+00:00","id":12945,"links":{},"metadata":{"_buckets":{"deposit":"e78cd938-4d85-46c4-a9aa-7d56c7cf2664"},"_deposit":{"id":"12945","owners":[],"pid":{"revision_id":0,"type":"depid","value":"12945"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00012945","sets":["499:960:961"]},"author_link":["40804"],"item_12_alternative_title_19":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"温熱ストレスによる骨格筋肥大における NF-κBとHSP72 の役割","subitem_alternative_title_language":"ja"}]},"item_12_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-03-25","bibliographicIssueDateType":"Issued"}}]},"item_12_date_granted_64":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2011-03-25"}]},"item_12_degree_grantor_62":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"名古屋大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"NAGOYA University"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"13901","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_12_degree_name_61":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(リハビリテーション療法学)","subitem_degreename_language":"ja"}]},"item_12_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Effects of heat stress on phosphorylated nuclear factor-κB (phospho-NF-κB) and tumor necrosis factor α (TNFα) contents in skeletal muscles were studied. Male Wistar rats (7-week-old) were randomly assigned to control and heat-stressed groups. Rats in heat-stressed group were exposed to heat stress (42°C for 60 min) in an incubator without anesthesia. Soleus muscles were dissected and weighted 1, 3, and 7 days after the heat exposure. Significant increases in the wet weight and protein content of soleus were observed 7 days following the exposure (p < 0.05). Heat stress also induced the up-regulation of heat shock protein 72 (HSP72), IκBα (inhibitor of NF-κB) and the increase in the relative population of Pax7-positive satellite cells to total muscle nuclei before the increase in muscle mass. The content levels of phospho-NF-κB and TNFα were significantly decreased 1 and 3 days after heat stress, respectively (p < 0.05). A negative correlation between HSP72 and phospho-NF-κB contents was observed 1 day after the heat exposure. These observations suggest that the decrease in NF-κB signaling may play a part of a role in heat stress-associated muscle hypertrophy.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_12_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"名古屋大学博士学位論文 学位の種類:博士(リハビリテーション療法学) (課程) 学位授与年月日:平成23年3月25日","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_12_dissertation_number_65":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第9070号"}]},"item_12_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/14840"}]},"item_12_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_12_text_63":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_text_value":"2010"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大野, 善隆","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"40804","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"k9070.pdf","filesize":[{"value":"287.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"k9070.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/12945/files/k9070.pdf"},"version_id":"35f204d6-10da-4222-b128-84a7c7a3db48"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"A possible role of  NF-κB and HSP72 in skeletal muscle hypertrophy induced by heat stress","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A possible role of  NF-κB and HSP72 in skeletal muscle hypertrophy induced by heat stress","subitem_title_language":"en"}]},"item_type_id":"12","owner":"1","path":["961"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-05-20"},"publish_date":"2011-05-20","publish_status":"0","recid":"12945","relation_version_is_last":true,"title":["A possible role of  NF-κB and HSP72 in skeletal muscle hypertrophy induced by heat stress"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T03:59:53.266826+00:00"}