{"created":"2021-03-01T06:20:28.798300+00:00","id":13451,"links":{},"metadata":{"_buckets":{"deposit":"01356890-01c0-42da-8718-845e78dcc526"},"_deposit":{"created_by":17,"id":"13451","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"13451"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00013451","sets":["499:508:509:1359"]},"author_link":["42164","42165","42166","42167","42168"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"78","bibliographicPageStart":"69","bibliographicVolumeNumber":"73","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The CD40 ligand/CD40 pathway is widely recognized for its prominent role in immune regulation and homeostasis. CD40, a member of the tumor necrosis factor receptor family, is expressed by antigenpresenting cells, as well as non-immune cells and tumors. The engagement of the CD40 and CD40 ligands, which are transiently expressed on T cells and other non-immune cells under inflammatory conditions, regulates a wide spectrum of molecular and cellular processes, including the initiation and progression of cellular and humoral adaptive immunity. Based on recent research findings, the engagement of the CD40 with a deregulated amount of CD40 ligand has been implicated in a number of inflammatory diseases. We will discuss the involvement of the CD40 ligand/CD40 interaction in the pathophysiology of inflammatory diseases, including autoimmune diseases, atherothrombosis, cancer, and respiratory diseases.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/15350"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.73.3-4.69","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7334/7334.html","subitem_relation_type_select":"URI"}}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN(Online)","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN(print)","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KAWABE, TSUTOMU","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"42164","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"MATSUSHIMA, MIYOKO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"42165","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"HASHIMOTO, NAOZUMI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"42166","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"IMAIZUMI, KAZUYOSHI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"42167","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"HASEGAWA, YOSHINORI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"42168","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"v73n34p69_78.pdf","filesize":[{"value":"457.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"v73n34p69_78.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/13451/files/v73n34p69_78.pdf"},"version_id":"612e2778-1055-4204-a579-1b634a9ec78c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"CD40","subitem_subject_scheme":"Other"},{"subitem_subject":"Immunity","subitem_subject_scheme":"Other"},{"subitem_subject":"B cells","subitem_subject_scheme":"Other"},{"subitem_subject":"Alveolar macrophages","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"CD40/CD40 LIGAND INTERACTIONS IN IMMUNE RESPONSES AND PULMONARY IMMUNITY","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"CD40/CD40 LIGAND INTERACTIONS IN IMMUNE RESPONSES AND PULMONARY IMMUNITY","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["1359"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-08-24"},"publish_date":"2011-08-24","publish_status":"0","recid":"13451","relation_version_is_last":true,"title":["CD40/CD40 LIGAND INTERACTIONS IN IMMUNE RESPONSES AND PULMONARY IMMUNITY"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T06:36:40.257435+00:00"}