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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 73(3-4)

CARDIOPROTECTIVE MECHANISMS OF LIFESTYLE MODIFICATIONS AND PHARMACOTHERAPIES ON CARDIAC REMODELING AND DYSFUNCTION IN HYPERTENSIVE HEART DISEASE: AN OVERVIEW

https://doi.org/10.18999/nagjms.73.3-4.91
https://doi.org/10.18999/nagjms.73.3-4.91
37ef3be8-8822-4db2-995e-170c23e4f4d4
名前 / ファイル ライセンス アクション
v73n34p91_105.pdf v73n34p91_105.pdf (772.4 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2011-08-24
タイトル
タイトル CARDIOPROTECTIVE MECHANISMS OF LIFESTYLE MODIFICATIONS AND PHARMACOTHERAPIES ON CARDIAC REMODELING AND DYSFUNCTION IN HYPERTENSIVE HEART DISEASE: AN OVERVIEW
著者 Nagata, Kohzo

× Nagata, Kohzo

WEKO 42170

Nagata, Kohzo

Search repository
Hattori, Takuya

× Hattori, Takuya

WEKO 42171

Hattori, Takuya

Search repository
キーワード
主題Scheme Other
主題 Cardioprotection
キーワード
主題Scheme Other
主題 Lifestyle modification
キーワード
主題Scheme Other
主題 Pharmacotherapy
キーワード
主題Scheme Other
主題 Hypertensive heart disease
抄録
内容記述 The incidence of cardiovascular events in hypertensive patients is clearly related to a left ventricular mass during treatment, and a regression of left ventricular hypertrophy is associated with a better prognosis. This is the case even independently of changes in other risk factors, including blood pressure. Evidence indicates that lifestyle modifications such as dietary salt restriction and weight loss are effective means in preventing the development of hypertension and reducing blood pressure and left ventricular mass in hypertensive patients. Salt restriction may also reduce the long-term risk of cardiovascular events. It has been recognized that the primary targets of current antihypertensive drugs are the renin-angiotensinaldosterone system, calcium homeostasis, the ionic transport mechanisms in the kidneys, and the sympathetic nervous system. Clinical as well as experimental studies have demonstrated the cardioprotective effects of antihypertensive drugs independently of their blood pressure lowering effects. Hypertension is often complicated by other disease states including diabetes, dyslipidemia, and ischemic heart disease. Some of the drugs used for the treatment of such complications are also shown to produce cardioprotective effects in addition to their original effects. We ought to better understand these pleiotropic effects for the most effective treatments of hypertension and its complications.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.73.3-4.91
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 73, 号 3-4, p. 91-105, 発行日 2011-08
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7334/7334.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/15352
識別子タイプ HDL
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