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CARDIOPROTECTIVE MECHANISMS OF LIFESTYLE MODIFICATIONS AND PHARMACOTHERAPIES ON CARDIAC REMODELING AND DYSFUNCTION IN HYPERTENSIVE HEART DISEASE: AN OVERVIEW
https://doi.org/10.18999/nagjms.73.3-4.91
https://doi.org/10.18999/nagjms.73.3-4.9137ef3be8-8822-4db2-995e-170c23e4f4d4
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
v73n34p91_105.pdf (772.4 kB)
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| アイテムタイプ | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2011-08-24 | |||||
| タイトル | ||||||
| タイトル | CARDIOPROTECTIVE MECHANISMS OF LIFESTYLE MODIFICATIONS AND PHARMACOTHERAPIES ON CARDIAC REMODELING AND DYSFUNCTION IN HYPERTENSIVE HEART DISEASE: AN OVERVIEW | |||||
| 言語 | en | |||||
| 著者 |
Nagata, Kohzo
× Nagata, Kohzo× Hattori, Takuya |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Cardioprotection | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Lifestyle modification | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Pharmacotherapy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Hypertensive heart disease | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The incidence of cardiovascular events in hypertensive patients is clearly related to a left ventricular mass during treatment, and a regression of left ventricular hypertrophy is associated with a better prognosis. This is the case even independently of changes in other risk factors, including blood pressure. Evidence indicates that lifestyle modifications such as dietary salt restriction and weight loss are effective means in preventing the development of hypertension and reducing blood pressure and left ventricular mass in hypertensive patients. Salt restriction may also reduce the long-term risk of cardiovascular events. It has been recognized that the primary targets of current antihypertensive drugs are the renin-angiotensinaldosterone system, calcium homeostasis, the ionic transport mechanisms in the kidneys, and the sympathetic nervous system. Clinical as well as experimental studies have demonstrated the cardioprotective effects of antihypertensive drugs independently of their blood pressure lowering effects. Hypertension is often complicated by other disease states including diabetes, dyslipidemia, and ischemic heart disease. Some of the drugs used for the treatment of such complications are also shown to produce cardioprotective effects in addition to their original effects. We ought to better understand these pleiotropic effects for the most effective treatments of hypertension and its complications. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.73.3-4.91 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7334/7334.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 73, 号 3-4, p. 91-105, 発行日 2011-08 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/15352 | |||||
| 識別子タイプ | HDL | |||||
