@article{oai:nagoya.repo.nii.ac.jp:00001386,
 author = {KAMIYA, Kaichiro and KODAMA, Itsuo and LU, Zhibo},
 issue = {1/2},
 journal = {Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University},
 month = {Dec},
 note = {Bepridil, a potent antiarrhythmic drug, inhibits a variety of cardiac ion channels. Specific block of bepridil on I_<Kr> or I_<Ks>, however, has been controversial and dependent on species and experimental conditions. To clarify this point, we studied the effects of bepridil on I& or I_<Ks> in rabbit ventricular myocytes. Bepridil caused a concentration-dependent inhibition on both currents. IC_<50>s were 0.43 ± 0.20 μM (n=5) for I& and 0.82 ± 0.32 (μM (n=7) for I_<Ks>. These results suggest that bepridil may thereby cause an antiarrhythmic action through an inhibition of both 1^ and I_<Ks>., 国立情報学研究所で電子化したコンテンツを使用している。},
 pages = {95--97},
 title = {Effects of Bepridil on I_<Kr> and I_<Ks> of Rabbit Ventricular Myocytes},
 volume = {46},
 year = {2002}
}