{"_buckets": {"deposit": "f544510a-5e3b-46f1-beb9-5537171c5982"}, "_deposit": {"id": "1387", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "1387"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00001387", "sets": []}, "author_link": ["3194", "3195", "3196", "3197", "3198", "3199", "3200", "3201"], "item_1615768549627": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_9_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2002-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1/2", "bibliographicPageEnd": "100", "bibliographicPageStart": "98", "bibliographicVolumeNumber": "46", "bibliographic_titles": [{"bibliographic_title": "Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University", "bibliographic_titleLang": "en"}]}]}, "item_9_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Recent studies using confocal microscopy combined with patch clamping on single sinoatrial (SA) node pacemaker cells suggest that Ca^\u003c2+\u003e release from the sarcoplasmic reticulum (SR) during diastole may play a prominent role in the late phase of pacemaker depolarization. The present study was designed to test this hypothesis in the intact SA node. We investigated the effects of a high concentration of ryanodine, which is known to disable SR Ca^\u003c2+\u003e release, on spontaneous activity of isolated rabbit right atrium including the whole SA node by using an extracellular potential mapping technique. Inhibition of SR Ca^\u003c2+\u003e release by 30 μM ryanodine caused only a moderate reduction of the spontaneous firing rate (by 20.0±2.8 %, n=4) of the intact SA node. This observation is inconsistent with previous data obtained from single pacemaker cells. Physiological significance of SR Ca^\u003c2+\u003e release in the regulation of SA node pacemaker activity is still unsettled.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_9_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "国立情報学研究所で電子化したコンテンツを使用している。", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/2797"}]}, "item_9_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/envm.46.98", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Research Institute of Environmental Medicine, Nagoya University", "subitem_publisher_language": "en"}]}, "item_9_select_15": 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[{"creatorName": "NIWA, Ryoko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3196", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "SHIBATA, Nitaro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3197", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "MITSUI, Kazuyuki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3198", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "BOYETT, Mark R.", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3199", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KAMIYA, Kaichiro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3200", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KODAMA, Itsuo", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3201", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00000034877.pdf", "filesize": [{"value": "268.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 268000.0, "url": {"label": "KJ00000034877.pdf", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/1387/files/KJ00000034877.pdf"}, "version_id": "12a47d6a-74ed-4e5c-acef-681b525bcd0d"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "sinoatrial node", "subitem_subject_scheme": "Other"}, {"subitem_subject": "pacemaker activity", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ryanodine", "subitem_subject_scheme": "Other"}, {"subitem_subject": "sarcoplasmic reticulum", "subitem_subject_scheme": "Other"}, {"subitem_subject": "extracellular potential mapping", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Role of Ca^\u003c2+\u003e Release from Sarcoplasmic Reticulum in Pacemaker Activity of the Sinoatrial Node", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Role of Ca^\u003c2+\u003e Release from Sarcoplasmic Reticulum in Pacemaker Activity of the Sinoatrial Node", "subitem_title_language": "en"}]}, "item_type_id": "9", "owner": "1", "path": ["335"], "permalink_uri": "https://doi.org/10.18999/envm.46.98", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2006-01-05"}, "publish_date": "2006-01-05", "publish_status": "0", "recid": "1387", "relation": {}, "relation_version_is_last": true, "title": ["Role of Ca^\u003c2+\u003e Release from Sarcoplasmic Reticulum in Pacemaker Activity of the Sinoatrial Node"], "weko_shared_id": -1}