{"created":"2021-03-01T06:07:45.164630+00:00","id":1391,"links":{},"metadata":{"_buckets":{"deposit":"e0aea4e3-a251-4268-9d04-31c995261989"},"_deposit":{"id":"1391","owners":[],"pid":{"revision_id":0,"type":"depid","value":"1391"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00001391","sets":["329:333:334:335"]},"author_link":["3224","3225","3226","3227","3228"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1/2","bibliographicPageEnd":"111","bibliographicPageStart":"109","bibliographicVolumeNumber":"46","bibliographic_titles":[{"bibliographic_title":"Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Our previous study showed that two components of the delayed rectifier potassium current, I_<Kr> and I_<Ks>, were heterogeneously distributed in right (RV) and left (LV) ventricles in rabbit hearts. However, the mechanisms of heterogeneous distribution of these channels were not known. In the present study, we investigated the encoding mRNA levels of I_<Kr> (ERG) and I_<Ks> (KVLQT1 and minK) in RV and LV. By using a quantitative real-time PCR method, we found mRNA levels were not significantly different between two ventricles in ERG (RV: 1103 ± 218 molecules/10^5 GAPDH molecules, LV: 886 ± 155, n=4), KVLQT1 (RV: 645 ± 113, LV: 509 + 170, n=4) and minK (RV: 209 ± 33, LV: 185 ± 47, n=4). These results suggest that heterogeneous distribution of I_<Kr> and I_<Ks> in RV and LV could not be explained by the mRNA levels in ventricles. Other unknown factor may underlie this phenomenon.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"国立情報学研究所で電子化したコンテンツを使用している。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_9_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/2801"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/envm.46.109","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Research Institute of Environmental Medicine, Nagoya University","subitem_publisher_language":"en"}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"02870517","subitem_source_identifier_type":"PISSN"}]},"item_9_text_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_text_value":"application/pdf"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"LU, Zhibo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3224","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"HOJO, Mayumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3225","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"YASUI, Kenji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3226","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KODAMA, Itsuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3227","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KAMIYA, Kaichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3228","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-16"}],"displaytype":"detail","filename":"KJ00000034881.pdf","filesize":[{"value":"257.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00000034881.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/1391/files/KJ00000034881.pdf"},"version_id":"e557b7b3-adbd-4f03-a486-52e56dd11b00"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"rabbit","subitem_subject_scheme":"Other"},{"subitem_subject":"RV and LV","subitem_subject_scheme":"Other"},{"subitem_subject":"delayed rectifier K^+ current","subitem_subject_scheme":"Other"},{"subitem_subject":"mRNA levels","subitem_subject_scheme":"Other"},{"subitem_subject":"regional distribution","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"mRNA Levels of ERG, KVLQT1 and minK in Rabbit Right and Left Ventricles","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"mRNA Levels of ERG, KVLQT1 and minK in Rabbit Right and Left Ventricles","subitem_title_language":"en"}]},"item_type_id":"9","owner":"1","path":["335"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2006-01-05"},"publish_date":"2006-01-05","publish_status":"0","recid":"1391","relation_version_is_last":true,"title":["mRNA Levels of ERG, KVLQT1 and minK in Rabbit Right and Left Ventricles"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-26T06:15:39.741420+00:00"}