@article{oai:nagoya.repo.nii.ac.jp:00001392, author = {WATANABE, Tadashi and IWASE, Satoshi and SAITO, Kiyoshi and NAGATANI, Tetsuya and YOSHIDA, Jun}, issue = {1/2}, journal = {Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University}, month = {Dec}, note = {In patients with suprasellar tumors, the tumor itself and also its surgical resection may produce hypothalamic dysfunction including thermoregulatory disturbances. We quantitatively evaluated skin sympathetic nerve activity (SSNA) using microneurography in eight patients with hypothalamic dysfunction following resection. SSNA, skin blood flow by laser Doppler, sweating, blood pressure, and pulse rate were monitored during changes of core (tympanic) temperature, in the patients and seven healthy controls. Core temperature was decreased by 0.3℃and increased by 0.5℃ relative to baseline using a cooling/heating blanket. Argumentation of SSNA by cooling did not differ between patients and controls. An increase of SSNA upon heating was absent in patients but present in controls. Skin blood flow during heating increased significantly in controls but not in patients. Our results indicated that the patients had impaired heat loss during body temperature elevation. Microneurography is a sensitive measure of hypothalamic autonomic function., 国立情報学研究所で電子化したコンテンツを使用している。}, pages = {112--115}, title = {Microneurographic Analysis of Sympathetic Outflow to the Skin in Patients with Postoperative Hypothalamic Dysfunction after Suprasellar Tumors}, volume = {46}, year = {2002} }