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A PERMISSION SYSTEM FOR CARBAPENEM USE REDUCED INCIDENCE OF DRUG-RESISTANT BACTERIA AND COST OF ANTIMICROBIALS AT A GENERAL HOSPITAL IN JAPAN
https://doi.org/10.18999/nagjms.74.1-2.93
https://doi.org/10.18999/nagjms.74.1-2.9392ab33e5-8ca4-46a8-a360-3b7e7115d514
名前 / ファイル | ライセンス | アクション |
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09_Ikeda.pdf (318.3 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2012-02-29 | |||||
タイトル | ||||||
タイトル | A PERMISSION SYSTEM FOR CARBAPENEM USE REDUCED INCIDENCE OF DRUG-RESISTANT BACTERIA AND COST OF ANTIMICROBIALS AT A GENERAL HOSPITAL IN JAPAN | |||||
言語 | en | |||||
著者 |
IKEDA, YOSHIAKI
× IKEDA, YOSHIAKI× MAMIYA, TAKAYOSHI× NISHIYAMA, HIDEKI× NARUSAWA, SHIHO× KOSEKI, TAKENAO× MOURI, AKIHIRO× NABESHIMA, TOSHITAKA |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Carbapenem | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Antimicrobial | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Permission system | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ATC/DDD system | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Drug-resistant bacteria | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Some drug management systems have been established in Japanese hospitals to reduce medical costs and regulate drug usage. Among the many available prescription drugs, antimicrobials should be given special attention because their inappropriate use often leads to sudden outbreaks of resistant bacteria. As drug specialists, pharmacists should monitor the use of all drugs, particularly antimicrobials. Carbapenems are a class of broad-spectrum antimicrobials that are widely used to treat infections worldwide. However, their inappropriate use has led to an increase in the incidence of drug-resistant bacteria and consequently, medical costs, at hospitals. To reduce inappropriate use and drug resistance, we have established a permission system to control the use of carbapenems at the Japanese Red Cross Nagoya Daiichi Hospital. In this study, we retrospectively evaluated the applicability of the new permission system compared to that of the notification system and the non control system for 14 months each. The two management systems were able to maintain total antibiotic use density and control the outbreak of drug-resistant bacteria (P. aeruginosa, E. coli, and K. pneumoniae). The number of carbapenem prescriptions was decreased dramatically when this permission system was enforced. Compared to the non control system, the cost of antimicrobials was reduced by $757,470 for the 14-month study period using the permission system. These results suggest that our system to control the use of antimicrobials can efficiently suppress the incidence of drug-resistant bacteria and medical costs at hospitals. | |||||
言語 | en | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.74.1-2.93 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7412/7412.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 74, 号 1-2, p. 93-104, 発行日 2012-02 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/16026 | |||||
識別子タイプ | HDL |