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Postprandial hypotension: hemodynamic differences between multiple system atrophy and peripheral autonomic neuropathy
http://hdl.handle.net/2237/16641
http://hdl.handle.net/2237/16641f8c4375a-0e79-4ac4-8c0b-a896c38945a8
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2012-06-29 | |||||
タイトル | ||||||
タイトル | Postprandial hypotension: hemodynamic differences between multiple system atrophy and peripheral autonomic neuropathy | |||||
言語 | en | |||||
著者 |
Hirayama, M
× Hirayama, M× Watanabe, H× Koike, Y× Hasegawa, Y× Kanaoke, Y× Sakurai, N× Hakusui, S× Takahashi, A |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | This is the author's version of a work that was accepted for publication in Journal of the Autonomic Nervous System. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms, may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of the Autonomic Nervous System. v.43, n.1, 1993, p.1–6 DOI: 10.1016/0165-1838(93)90315-L | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Postprandial hypotension | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cardiac output | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hemodynamics | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Multiple system atrophy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Autonomic neuropathy | |||||
抄録 | ||||||
内容記述 | To clarify the mechanism of postprandial hypotension (PPH), we performed hemodynamic investigation after oral glucose ingestion in ten patients with multiple system atrophy (MSA), three patients with peripheral autonomic neuropathy (PN) and 16 normal controls. Blood pressure (BP) and heart rate (HR) were measured with an automatic sphygmomanometer; cardiac out (CO) and lower leg blood flow (LBF) with impedance plethysmography; and portal blood flow (PBF) using a B-mode pulse Doppler. In normal subjects, BP, LBF and vascular resistance of the lower leg (LVR) were not changed, but HR slightly increased, and PBF and CO significantly increased after oral ingestion of 75 g glucose. In the patients with MSA, BP fell significantly 15 min after glucose ingestion, and HR and CO did not increase. PBF and LBF increased and LVR fell significantly. In PN patients, BP decreased at 15 min after glucose ingestion, but soon recovered. Increase of PBF and decrease of LVR in them were almost similar to those in the MSA group, and increase of CO was greater than that in the controls. These results suggest that both systemic vasodilatation (presumably due to gastrointestinal vasodilatatory peptides) and lack of compensatory increase of CO and LVR play important roles in PPH. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | 名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成5年1月28日 平山正昭氏の博士論文として提出された | |||||
言語 | ja | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Elsevier | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_db06 | |||||
タイプ | doctoral thesis | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/0165-1838(93)90315-L | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0165-1838 | |||||
書誌情報 |
en : Journal of the Autonomic Nervous System 巻 43, 号 1, p. 1-6, 発行日 1993-04 |
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学位名 | ||||||
言語 | ja | |||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 13901 | |||||
言語 | ja | |||||
学位授与機関名 | 名古屋大学 | |||||
言語 | en | |||||
学位授与機関名 | NAGOYA University | |||||
学位授与年度 | ||||||
学位授与年度 | 1993 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 1993-04-01 | |||||
学位授与番号 | ||||||
学位授与番号 | 乙第4331号 | |||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://dx.doi.org/10.1016/0165-1838(93)90315-L | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/16641 | |||||
識別子タイプ | HDL |