{"created":"2021-03-01T06:21:55.517984+00:00","id":14785,"links":{},"metadata":{"_buckets":{"deposit":"cddc973c-cf11-4051-928e-ef79d0a7b172"},"_deposit":{"id":"14785","owners":[],"pid":{"revision_id":0,"type":"depid","value":"14785"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00014785","sets":["499:960:1165"]},"author_link":["45658","45659","45660","45661","45662"],"item_12_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"659","bibliographicPageStart":"657","bibliographicVolumeNumber":"49","bibliographic_titles":[{"bibliographic_title":"Journal of Clinical Pathology","bibliographic_titleLang":"en"}]}]},"item_12_date_granted_64":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"1996-08-01"}]},"item_12_degree_grantor_62":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"名古屋大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"NAGOYA University"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"13901","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_12_degree_name_61":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)","subitem_degreename_language":"ja"}]},"item_12_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"AIMS: To correlate the expression of proliferating cell nuclear antigen (PCNA) with various clinicopathological features of papillary thyroid carcinoma. METHODS: Sections from 131 formalin fixed, paraffin wax embedded papillary thyroid carcinomas were stained with a monoclonal antibody (PC10) directed against PCNA using the avidin-biotin immunoperoxidase (ABC) method. PCNA immunoreactivity was based on the PCNA labelling index (LI) following evaluation of at least 1000 tumour cells, and expressed as follows: grade A (LI < 10%), grade B (10% < or = LI < 25%), and grade C (LI > or = 25%). The relation between PCNA expression in these three groups and other clinicopathological factors, such as sex, age, tumour size, nodal metastases, and histological differentiation, were examined. RESULTS: Based on the labelling index, 57 (43.5%) cases were graded as A, 46 (35.1%) as B, and 28 (21.4%) as C. The female-:male ratios were 6.13:1 for group A, 2.83:1 for group B, and 2.11:1 for group C. The mean (SD) ages of the patients were 39.0 (16.1) in group A, 53.5 (14.4) in group B, and 55.8 (13.3) years in group C. The correlation between age and PCNA grade was strongest in women. CONCLUSIONS: PCNA immunoreactivity is correlated with sex and age in patients with papillary thyroid tumours.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_12_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成9年2月20日 安藤広幸氏の博士論文として提出された","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_12_dissertation_number_65":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"乙第5153号"}]},"item_12_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/16718"}]},"item_12_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"the BMJ Publishing Group","subitem_publisher_language":"en"}]},"item_12_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_12_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0021-9746","subitem_source_identifier_type":"PISSN"}]},"item_12_text_63":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_text_value":"1996"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ando, H","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"45658","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Funahashi, H","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"45659","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ito, M","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"45660","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Imai, T","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"45661","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takagi, H","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"45662","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"o5153.pdf","filesize":[{"value":"741.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"o5153.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/14785/files/o5153.pdf"},"version_id":"8b504867-5f18-4f12-b460-91a72cbb4909"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Proliferating cell nuclear antigen expression in papillary thyroid carcinoma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Proliferating cell nuclear antigen expression in papillary thyroid carcinoma","subitem_title_language":"en"}]},"item_type_id":"12","owner":"1","path":["1165"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2012-08-21"},"publish_date":"2012-08-21","publish_status":"0","recid":"14785","relation_version_is_last":true,"title":["Proliferating cell nuclear antigen expression in papillary thyroid carcinoma"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T04:02:12.238667+00:00"}