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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 74(3-4)

ASSOCIATION OF OBESITY AND DIABETES WITH SERUM PROSTATE-SPECIFIC ANTIGEN LEVELS IN JAPANESE MALES

https://doi.org/10.18999/nagjms.74.3-4.285
https://doi.org/10.18999/nagjms.74.3-4.285
d758d33e-53c4-4ac6-990f-b7c1f00b9973
名前 / ファイル ライセンス アクション
07_Naito.pdf 07_Naito.pdf (207.6 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2012-08-29
タイトル
タイトル ASSOCIATION OF OBESITY AND DIABETES WITH SERUM PROSTATE-SPECIFIC ANTIGEN LEVELS IN JAPANESE MALES
著者 NAITO, MARIKO

× NAITO, MARIKO

WEKO 45758

NAITO, MARIKO

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ASAI, YATAMI

× ASAI, YATAMI

WEKO 45759

ASAI, YATAMI

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MORI, ATSUYOSHI

× MORI, ATSUYOSHI

WEKO 45760

MORI, ATSUYOSHI

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FUKADA, YUKO

× FUKADA, YUKO

WEKO 45761

FUKADA, YUKO

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KUWABARA, MAYUMI

× KUWABARA, MAYUMI

WEKO 45762

KUWABARA, MAYUMI

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KATASE, SHIRO

× KATASE, SHIRO

WEKO 45763

KATASE, SHIRO

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HISHIDA, ASAHI

× HISHIDA, ASAHI

WEKO 45764

HISHIDA, ASAHI

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MORITA, EMI

× MORITA, EMI

WEKO 45765

MORITA, EMI

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KAWAI, SAYO

× KAWAI, SAYO

WEKO 45766

KAWAI, SAYO

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OKADA, RIEKO

× OKADA, RIEKO

WEKO 45767

OKADA, RIEKO

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NISHIO, KAZUKO

× NISHIO, KAZUKO

WEKO 45768

NISHIO, KAZUKO

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TAMAKOSHI, AKIKO

× TAMAKOSHI, AKIKO

WEKO 45769

TAMAKOSHI, AKIKO

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WAKAI, KENJI

× WAKAI, KENJI

WEKO 45770

WAKAI, KENJI

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HAMAJIMA, NOBUYUKI

× HAMAJIMA, NOBUYUKI

WEKO 45771

HAMAJIMA, NOBUYUKI

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キーワード
主題Scheme Other
主題 Prostate-specific antigen
キーワード
主題Scheme Other
主題 Diabetes mellitus
キーワード
主題Scheme Other
主題 Obesity
キーワード
主題Scheme Other
主題 Body mass index
キーワード
主題Scheme Other
主題 Epidemiology
抄録
内容記述 Patients with diabetes have been reported to be at an increased risk for cancers of the pancreas, liver, and colon; however, recent studies have suggested that men with diabetes are at a decreased risk for prostate cancer. Previous studies have found that obese men have lower serum prostate-specific antigen (PSA) concentrations than do non-obese men. Further understanding of how obesity and diabetes affect the PSA concentration may improve our ability to detect clinically relevant prostate tumors. This study examined the relationships among serum PSA level, obesity, and diabetes in apparently healthy Japanese males. We analyzed the baseline data from 2,172 Japanese males (age, 56.8 ± 6.1 years [mean ± SD]) who participated in the Japan Multi-Institutional Collaborative Cohort Study. Diabetes was defined as the presence of both a hemoglobin A1c (JDS) of ≥6.1% and a fasting plasma glucose level of ≥126 mg/dL, or a positive medical history. After adjusting for age, the PSA levels were elevated among males with a higher normal BMI (ranging from 23.0 to 24.9) and lowered among men with a BMI of ≥25.0. In the stratified analysis, these significant differences in BMI categories were absent among diabetics. The mean PSA levels were significantly lower in diabetics than in non-diabetics among subjects aged 60 and over. Our findings suggest that the pre-overweight men had increased PSA levels, and the diabetes was associated with a reduction of PSA levels in elderly.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.74.3-4.285
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 74, 号 3-4, p. 285-292, 発行日 2012-08
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7434/7434.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/16739
識別子タイプ HDL
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