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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 37(1-2)

Clinical Evaluation of Antibody Sensitized Latex Particltes Method for Australia Antigen in Serum

https://doi.org/10.18999/nagjms.37.1-2.29
https://doi.org/10.18999/nagjms.37.1-2.29
3b47f99e-df93-4fbd-a229-1bf9440bb0e3
名前 / ファイル ライセンス アクション
v37n12p29_32.pdf v37n12p29_32.pdf (251.6 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-01-18
タイトル
タイトル Clinical Evaluation of Antibody Sensitized Latex Particltes Method for Australia Antigen in Serum
著者 OHYA, TAKAHIKO

× OHYA, TAKAHIKO

WEKO 46628

OHYA, TAKAHIKO

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OHYA, FUMIHIKO

× OHYA, FUMIHIKO

WEKO 46629

OHYA, FUMIHIKO

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TOMIMURA, KOUICHI

× TOMIMURA, KOUICHI

WEKO 46630

TOMIMURA, KOUICHI

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抄録
内容記述 There are several testing methods for the detection of Australia antigen. Among them an antibody sensitized latex particle agglutination assay (LAT) for the detection is technologically simple, sensitive, and rapid. So the detection of the antigen in the 896 specimens from hepatic diseases was carried out by LAT, IEOP, and SRID and the detection of rheumatoid factor in the LAT positives was also made by the modified method of Heller et al. The results of testing the 896 specimens from blood donors are positive in 0.8%. negative in 4.1%. false positive in 5.1%. and false negative in 0.1%. And also. it is suggested that false positive to LAT is partially due to rheumatoid factor. since 7 specimens of 9 positives for rheumatoid factor were to LAT (a rate of 67.8%). and partially due to the freshness of blood, since of 59 storage specimens at 4°C for a week there were different reactions in 21 specimens between storage specimens and fresh specimens. Two false negatives in the 61 specimens from hepatic diseases showed positive reactions in diluted specimens for LAT. The cause of false negative reactions to LAT is unclear but it may partly be due to the rheumatoid factor and other factors. These results led us to the conclusions that the LAT requires further development and that the LAT appears to be useful as a preliminary screening for detection of the antigen.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.37.1-2.29
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 37, 号 1-2, p. 29-32, 発行日 1974-08
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/3712/3712.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/17296
識別子タイプ HDL
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