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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 37(3-4)

Histochemical Study on the Activity of the Enzymes in Human Hepatomas

https://doi.org/10.18999/nagjms.37.3-4.45
https://doi.org/10.18999/nagjms.37.3-4.45
3142ecc7-ced4-4deb-828f-b83cac820d70
名前 / ファイル ライセンス アクション
v37n34p45_57.pdf v37n34p45_57.pdf (1.5 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-01-18
タイトル
タイトル Histochemical Study on the Activity of the Enzymes in Human Hepatomas
著者 KOBAYASHI, HISANDO

× KOBAYASHI, HISANDO

WEKO 46632

KOBAYASHI, HISANDO

Search repository
TAUCHI, HISASHI

× TAUCHI, HISASHI

WEKO 46633

TAUCHI, HISASHI

Search repository
抄録
内容記述 Ten cases of human hepatoma obtained at surgery and autopsy were studied enzyme-histochemically, and compared with gastric carcinoma, intrahepatic bile duct carcinoma and prostate carcinoma. The enzymes studied were glucose-6-phosphatase, acid phosphatase, alkaline phosphatase, succinic dehydrogenase, cytochrome oxidase, and peroxidase. In conventional stained sections, case 1 was grade I and II hepatocellular carcinoma by the classification of Edmondson. Case 2 and case 3 were grade IV or more malignant than grade III, and the remaining were almost all grade III. Case 1, in which all enzymes except alkaline phosphatase were histochemically demonstrated in hepatoma cells, could belong to such minimum deviation hepatoma. Acid phosphatase was demonstrated as more prominent granules in the hepatocellular carcinoma cells of all cases. Succinic dehydrogenase was noticed to be very weak or negative except for case 1, but cytochrome oxidase was positive in all cases. Glucose-6-phosphatase was histochemically demonstrated in all cases examined, but the activity was low except for case 1, and negative in control cancer cases. Peroxidase was generally low in activity in all hepatomas except for case 1. The intensity of glucose-6-phosphatase and peroxidase activities in the present human hepatomas may be related to a more detailed and accurate differentiation of hepatocellular carcinoma than the classification of Edmondson by conventional stained sections.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.37.3-4.45
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 37, 号 3-4, p. 45-57, 発行日 1975-03
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/3734/3734.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/17298
識別子タイプ HDL
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