{"created":"2021-03-01T06:22:28.952490+00:00","id":15305,"links":{},"metadata":{"_buckets":{"deposit":"cff515b4-e29d-4ef9-9e1f-10369f86b122"},"_deposit":{"created_by":17,"id":"15305","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"15305"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00015305","sets":["499:508:509:1441"]},"author_link":["46691"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1977-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"31","bibliographicPageStart":"21","bibliographicVolumeNumber":"39","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"An improved radiochemical method to measure the δ-aminoJevulinic acid (ALA) synthetase activity in human bone marrow erythroblasts by incubating bone marrow cell homogenate with 14C-succinate and succinyl CoA generating system has been reported. Studies were made to obtain the optimal conditions for the enzyme assay and to confirm the reliability of the assay procedures.\nALA-synthetase in erythroblasts was found to be decreased in all 3 cases of iron deficiency anemia and 3 cases of β-thalassemia minor. In 5 cases of idiopathic sideroblastic anemia, the enzyme activity was markedly decreased. A case of sideroblastic anemia, who restored normal erythropoiesis following the administration of pyridoxal phosphate (PLP) showed low PLP level in serum & blood as well as in vivo evidence of PLP deficiency and an in vitro stimulation of ALAsynthetase activity by PLP. Erythroblasts of 4 patients with erythroleukemia showed diminished bone marrow ALA-synthetase activity.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/17322"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.39.1-2.21","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/3912/3912.html","subitem_relation_type_select":"URI"}}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN（Online）","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"TANAKA, MASAO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"46691","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"v39n12p21_31.pdf","filesize":[{"value":"734.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"v39n12p21_31.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/15305/files/v39n12p21_31.pdf"},"version_id":"703d9ca9-89c1-4632-851e-3591caaf1600"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Bone Marrow δ-Aminolevulinic Acid Synthetase Activity in Hematological Disorders","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Bone Marrow δ-Aminolevulinic Acid Synthetase Activity in Hematological Disorders","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["1441"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-01-21"},"publish_date":"2013-01-21","publish_status":"0","recid":"15305","relation_version_is_last":true,"title":["Bone Marrow δ-Aminolevulinic Acid Synthetase Activity in Hematological Disorders"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T06:03:11.558846+00:00"}