@article{oai:nagoya.repo.nii.ac.jp:00015370, author = {SHIBATA, MASAO and KAWANISHI, ATSUKO and KISHI, TSUNEKI and KOBAYASHI, KAIZO and KUNO, TSUNEJI and SASAKI, MAKOTO and YASUDA, BUNJI}, issue = {3-4}, journal = {Nagoya Journal of Medical Science}, month = {Mar}, note = {Elastase is an elastin lytic enzyme that inhibits the deposition of fat on arterial walls and suppresses fat buildup. The changes in the renal glomerular basement membrane were observed over 30days of elastase administration in N. Y. S. mice (experimental congenital diabetic animals), and the treated group showed a lessening in the thickening of the basement membrane. The thichness of the basement membrane in treated animals was 2158.7 ± 96.2 Å against 2743.8 ± 168.6 Å in the control. Thus, a significant difference (P < 0.01) resulted between the groups of N. S. Y. mice, and elastase is presumed to act upon the metabolism of the renal glomerular basement membrane in them.}, pages = {111--115}, title = {Inhibitory Effect of Elastase on the Glomerular Capillary Basement Membrane Thickening of the Experimental Congenital Diabetic Mice (N.S.Y. Mice)}, volume = {43}, year = {1981} }