@article{oai:nagoya.repo.nii.ac.jp:00015388, author = {TOSAKI, FUJIO and YUASA, HIROMI and KAGEYAMA, NAOKI}, issue = {1-2}, journal = {Nagoya Journal of Medical Science}, month = {Nov}, note = {To investigate whether different types of neurons have a different threshold for seizure activity, the thresholds of two types of neurons in the hippocampal formation of a guinea pig, i.e., the CA3 cells in the hippocampus proper, and the granule cells in the dentate gyrus, were compared for penicillin-induced seizure activity using slice preparation. A change in the evoked population spikes recorded from the cell body layers in the slice was observed following perfusion of penicillin-containing medium. All of the CA3 cell body layers showed seizure activity at a penicillin concentration of 200 I.U./ml. The granule cell body layers did not show seizure acitvity even at the higher concentration of 500 I.U./ml.}, pages = {37--42}, title = {Threshold for Penicillin Induced Seizure in Hippocampal Slice}, volume = {45}, year = {1982} }