{"created":"2021-03-01T06:22:38.393002+00:00","id":15451,"links":{},"metadata":{"_buckets":{"deposit":"60c40a2e-2811-4796-a981-9a366bad0184"},"_deposit":{"created_by":17,"id":"15451","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"15451"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00015451","sets":["499:508:509:1456"]},"author_link":["98700","98701","98702"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1984-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-4","bibliographicPageEnd":"123","bibliographicPageStart":"117","bibliographicVolumeNumber":"46","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The production of gamma interferon (IFN-γ) by peripheral blood lymphocytes was studied in 38 patients with gastric cancer. Purified protein derivative (PPD) as a specific antigen and three kinds of mitogens, phytohemagglutinin-P (PHA), concanavalin A (Con A) and pokeweed mitogen (PWM), were used as IFN-γ inducers. IFN-γ production by lymphocytes was markedly reduced in patients with gastric cancer when these inducers were used. Reduction of IFN-γ production was observed more often in patients of Stage IV than in those of Stage I when PPD or Con A was used. PPD-induced IFN-γ production significantly increased in patients who were operated on curatively, while it decreased in those who were operated on noncuratively. IFN-γ production by lymphocytes, especially when PPD is used as an IFN-γ inducer, reflects cell-mediated immunity in patients with gastric cancer. It may be useful as quantitative parameter to predict therapeutic effects and prognosis in cancer patients.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.46.1-4.117","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4614/4614.html","subitem_relation_type_select":"URI"}}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN（Online）","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KUSUGAMI, KAZUO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"98700","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"MORISE, KIMITOMO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"98701","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KATO, HAJIME","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"98702","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"v46n14p117_123.pdf","filesize":[{"value":"532.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"v46n14p117_123.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/15451/files/v46n14p117_123.pdf"},"version_id":"9dd50f65-9585-49df-9f17-5e268f72354b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Gamma Interferon","subitem_subject_scheme":"Other"},{"subitem_subject":"Gastric Cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"Cell-mediated Immunity","subitem_subject_scheme":"Other"},{"subitem_subject":"Quantitative Parameter","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Gamma Interferon Production by Peripheral Blood Lymphocytes in Patients with Gastric Cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Gamma Interferon Production by Peripheral Blood Lymphocytes in Patients with Gastric Cancer","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["1456"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-02-08"},"publish_date":"2013-02-08","publish_status":"0","recid":"15451","relation_version_is_last":true,"title":["Gamma Interferon Production by Peripheral Blood Lymphocytes in Patients with Gastric Cancer"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T05:48:56.746772+00:00"}