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Different Mechanisms are Involved in 3H-Androgen Uptake by the Rat Seminiferous and Epididymal Tubules in vivo
https://doi.org/10.18999/nagjms.53.1-4.33
https://doi.org/10.18999/nagjms.53.1-4.33a4db5529-c2df-4d25-8ef9-f060615fe67a
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-02-14 | |||||
タイトル | ||||||
タイトル | Different Mechanisms are Involved in 3H-Androgen Uptake by the Rat Seminiferous and Epididymal Tubules in vivo | |||||
著者 |
YAMAMOTO, MASANORI
× YAMAMOTO, MASANORI× NAGAI, TATSUYA× MIYAKE, KOJI |
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キーワード | ||||||
主題Scheme | Other | |||||
主題 | Testosterone | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Testis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Epididymis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Micropuncture | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Microperifusion | |||||
抄録 | ||||||
内容記述 | Proluminal movement of 3H-androgen from peritubular to intratubular fluids of the adult rat testis and epididymis was investigated by using in vivo microperifusion and subsequent micropuncture of seminiferous tubules and caput, corpus, and cauda epididymal tubules. Tubules were perifused with Minimum Essential Medium containing 3H-testosterone. 14C-polyethyleneglycol was included in the perifusion fluid as a marker for contamination of intraluminal fluid by peritubular fluid. Radioactivity of isotopes in interstitial and intraluminal fluids was determined at 1 and 2 hours after perifusion and the percentage of peritubular isotopes appearing in the intraluminal fluid was determined. Proluminal movement of 3H-androgen across the seminiferous epithelium was significantly restricted. In contrast, intraluminal 3H-androgen concentrations in the caput epididymal fluid were 200-300% of those in the peritubular fluid at both 1 and 2 hours after perifusion. Similar results were found in the corpus epididymis. 3H-androgen concentrations in the cauda epididymal fluid were approximately 125% of the peritubular isotope concentrations. The exact mechanism underlying this uphill transepithelial movement of 3H-androgen in the rat epididymis continues to be elucidated. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.53.1-4.33 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 53, 号 1-4, p. 33-41, 発行日 1991-03 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5314/5314.html | |||||
識別子タイプ | URI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/17517 | |||||
識別子タイプ | HDL |