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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 55(1-4)

Cerebellar Hypoplasia in the Hyperbilirubinemic Gunn Rat: Morphological Aspects

https://doi.org/10.18999/nagjms.55.1-4.11
https://doi.org/10.18999/nagjms.55.1-4.11
c2b99887-83c9-45fe-9a8c-3ae49d67171f
名前 / ファイル ライセンス アクション
v55n14p11_21.pdf v55n14p11_21.pdf (1.7 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-02-14
タイトル
タイトル Cerebellar Hypoplasia in the Hyperbilirubinemic Gunn Rat: Morphological Aspects
著者 YAMAMURA, HIDEKI

× YAMAMURA, HIDEKI

WEKO 98822

YAMAMURA, HIDEKI

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TAKAGISHI, YOSHIKO

× TAKAGISHI, YOSHIKO

WEKO 98823

TAKAGISHI, YOSHIKO

Search repository
キーワード
主題Scheme Other
主題 Gunn rats
キーワード
主題Scheme Other
主題 Bilirubin
キーワード
主題Scheme Other
主題 Cerebellar hypoplasia
キーワード
主題Scheme Other
主題 Purkinje cells
キーワード
主題Scheme Other
主題 Synaptogenesis
抄録
内容記述 Gunn rats, a mutant strain of rats, suffer from autosomal recessive hyperbilirubinemia. The homozygotes (j/j) develop jaundice soon after birth and often exhibit kernicterus and cerebellar hypoplasia that are due to bilirubin. Therefore, j/j Gunn rats have been used as an animal model of bilirubin encephalopathy, as well as of neonatal hyperbilirubinemia. In this review, we discuss morphological aspects of the cerebellar hypoplasia that is due to bilirubin and describe the relationship between plasma bilirubin levels and cerebellar hypoplasia, as well as the pathogenesis of cerebellar hypoplasia, including abnormal histogenesis of the cerebellar cortex, abnormalities associated with Purkinje cells and abnormal synaptogenesis in j/j Gunn rats.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.55.1-4.11
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5514/5514.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 55, 号 1-4, p. 11-21, 発行日 1993-03
著者版フラグ
値 publisher
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