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The Regulation of Sleep and Wakefulness by the Hypothalamic Neuropeptide Orexin/Hypocretin
https://doi.org/10.18999/nagjms.75.1-2.29
https://doi.org/10.18999/nagjms.75.1-2.29c2041816-4bd7-4a0b-bde7-cfe6512aceb3
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-03-01 | |||||
タイトル | ||||||
タイトル | The Regulation of Sleep and Wakefulness by the Hypothalamic Neuropeptide Orexin/Hypocretin | |||||
著者 |
INUTSUKA, AYUMU
× INUTSUKA, AYUMU× YAMANAKA, AKIHIRO |
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キーワード | ||||||
主題Scheme | Other | |||||
主題 | orexin/hypocretin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | sleep | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hypothalamus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | optogenetics | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | neuropeptide | |||||
抄録 | ||||||
内容記述 | Orexins, also known as hypocretins, are neuropeptides that are exclusively expressed by neurons in the lateral hypothalamic area. Although originally recognized as regulators of feeding behavior, orexins are now mainly regarded as key modulators of the sleep/wakefulness cycle. In addition, anatomical studies of neural networks and analyses of transgenic mice have revealed integrated roles for orexin neurons in the coordination of emotion, energy homeostasis, and the reward system. A functional link between the limbic system and orexin neurons may be important for increasing vigilance in response to emotional stimuli. These findings suggest that orexin neurons relay information about an organism’s environment to maintain the proper amount of sleep and wakefulness in animals. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.75.1-2.29 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0027-7622 | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 75, 号 1-2, p. 29-36, 発行日 2013-02 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7512/7512.html | |||||
識別子タイプ | URI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/17598 | |||||
識別子タイプ | HDL |