{"_buckets": {"deposit": "4b637e69-159e-4ccf-bfe9-91f6b3b8bc58"}, "_deposit": {"id": "16458", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "16458"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00016458"}, "item_9_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2013-08", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3-4", "bibliographicPageEnd": "261", "bibliographicPageStart": "255", "bibliographicVolumeNumber": "75", "bibliographic_titles": [{"bibliographic_title": "Nagoya Journal of Medical Science"}]}]}, "item_9_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "A simple and rapid method for determination of nicotine and cotinine levels in urine was developed using samples prepared by micro-extraction by packed sorbent (MEPS) and subjected to gas chromatography- mass spectrometry (GC-MS) analysis. This method provided good reproducibility, as well as good linearity of calibration curves in the range of 1\u2013100 and 50\u20131000 ng/mL for quality control samples spiked with nicotine and cotinine, respectively. The detection limit of nicotine and cotinine was as low as 0.25 and 20 ng/mL, respectively. An evaporation procedure is not suitable for nicotine determination, thus an advantage of the present MEPS assay method is direct testing with GC-MS without the need for evaporation to a dry solvent. Our findings show that it may be useful for determining nicotine levels in various types of research studies.", "subitem_description_type": "Abstract"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "URI", "subitem_identifier_uri": "http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7534/7534.html"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/18475"}]}, "item_9_identifier_registration": {"attribute_name": "ID\u767b\u9332", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/nagjms.75.3-4.255", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Nagoya University School of Medicine"}]}, "item_9_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "0027-7622", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Iwai, Masae"}], "nameIdentifiers": [{"nameIdentifier": "49253", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ogawa, Tadashi"}], "nameIdentifiers": [{"nameIdentifier": "49254", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hattori, Hideki"}], "nameIdentifiers": [{"nameIdentifier": "49255", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Zaitsu, Kei"}], "nameIdentifiers": [{"nameIdentifier": "49256", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishii, Akira"}], "nameIdentifiers": [{"nameIdentifier": "49257", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, Osamu"}], "nameIdentifiers": [{"nameIdentifier": "49258", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Seno, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "49259", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "11_Ogawa.pdf", "filesize": [{"value": "193.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 193200.0, "url": {"label": "11_Ogawa.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/16458/files/11_Ogawa.pdf"}, "version_id": "8086879a-33fc-43f8-82e6-87c3bfa2ebb3"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "micro-extraction by packed sorbent (MEPS)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "gas chromatography-mass spectrometry (GC-MS)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "nicotine", "subitem_subject_scheme": "Other"}, {"subitem_subject": "cotinine", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "SIMPLE AND RAPID ASSAY METHOD FOR SIMULTANEOUS QUANTIFICATION OF URINARY NICOTINE AND COTININE USING MICRO-EXTRACTION BY PACKED SORBENT AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "SIMPLE AND RAPID ASSAY METHOD FOR SIMULTANEOUS QUANTIFICATION OF URINARY NICOTINE AND COTININE USING MICRO-EXTRACTION BY PACKED SORBENT AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY"}]}, "item_type_id": "9", "owner": "1", "path": ["499/508/509/1504"], "permalink_uri": "https://doi.org/10.18999/nagjms.75.3-4.255", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2013-09-12"}, "publish_date": "2013-09-12", "publish_status": "0", "recid": "16458", "relation": {}, "relation_version_is_last": true, "title": ["SIMPLE AND RAPID ASSAY METHOD FOR SIMULTANEOUS QUANTIFICATION OF URINARY NICOTINE AND COTININE USING MICRO-EXTRACTION BY PACKED SORBENT AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY"], "weko_shared_id": null}